Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | SFN | P31947 | 2/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | JAK3 | P52333 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | CHRND | Q07001 | 6/20 | 0.44 |
| ▸ | CHRNA1 | P02708 | 2/20 | 0.44 |
| ▸ | CHRNG | P07510 | 2/20 | 0.44 |
| ▸ | CHRNB1 | P11230 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7515768 | 0.91 | PTGS2 (0.51) | MEN1GAAKMT2APTGS2JAK3 | |
| SCHEMBL7520851 | 0.91 | PTGS2 (0.51) | MEN1GAAKMT2APTGS2JAK3 | |
| SCHEMBL7563980 | 0.91 | MEN1 (0.55) | MEN1GAAKMT2ASFNPTGS2 | |
| SCHEMBL7709387 | 0.88 | CTSL (0.55) | MEN1GAAKMT2ASFNPTGS2 | |
| SCHEMBL7557432 | 0.84 | CA1 (0.54) | MEN1GAAKMT2ACA1CA2 | |
| SCHEMBL7517509 | 0.84 | CTSL (0.59) | MEN1GAAKMT2ACA1CA2 | |
| SCHEMBL7703692 | 0.84 | L3MBTL1 (0.57) | MEN1GAAKMT2APTGS2JAK3 | |
| SCHEMBL7554886 | 0.82 | GRIA1 (0.55) | GAACHRNDCHRNA1CHRNGCHRNB1 | |
| SCHEMBL7709592 | 0.81 | MEN1 (0.80) | MEN1GAAKMT2APTGS2JAK3 | |
| SCHEMBL7712131 | 0.81 | CTSL (0.54) | MEN1GAAKMT2APTGS2JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6362165-B1 | Hydroxyphenyl derivatives with HIV integrase inhibitory properties | PHARMACOR INC. (CA) | 2002-03-26 | — | — | US | disclosed |