Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.47 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | JAK3 | P52333 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | SFN | P31947 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 5/20 | 0.44 |
| ▸ | CA2 | P00918 | 5/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.44 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7515768 | 0.92 | PTGS2 (0.51) | MEN1GAAKMT2APTGS2JAK3 | |
| SCHEMBL7520851 | 0.92 | PTGS2 (0.51) | MEN1GAAKMT2APTGS2JAK3 | |
| SCHEMBL7709781 | 0.91 | MEN1 (0.56) | MEN1GAAKMT2AERCC1ERCC4 | |
| SCHEMBL7709387 | 0.89 | CTSL (0.55) | MEN1GAAKMT2APTGS2JAK3 | |
| SCHEMBL7517509 | 0.85 | CTSL (0.59) | MEN1GAAKMT2ACTSLCA1 | |
| SCHEMBL7703692 | 0.85 | L3MBTL1 (0.57) | MEN1GAAKMT2AERCC1ERCC4 | |
| SCHEMBL7554729 | 0.85 | CTSL (0.55) | CTSLCA1CA2GRIA1LNPEP | |
| SCHEMBL7516942 | 0.83 | CTSL (0.53) | ERCC1ERCC4CTSLCA1CA2 | |
| SCHEMBL7712131 | 0.82 | CTSL (0.54) | MEN1GAAKMT2APTGS2JAK3 | |
| SCHEMBL7709355 | 0.81 | ESRRG (0.51) | MEN1GAAKMT2APTGS2JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6362165-B1 | Hydroxyphenyl derivatives with HIV integrase inhibitory properties | PHARMACOR INC. (CA) | 2002-03-26 | — | — | US | disclosed |
| EP-1165492-A1 | HYDROXYPHENYL DERIVATIVES WITH HIV INTEGRASE INHIBITORY PROPERTIES | Pharmacor Inc. (CA) | 2002-01-02 | — | — | EP | disclosed |
| WO-2000059867-A1 | HYDROXYPHENYL DERIVATIVES WITH HIV INTEGRASE INHIBITORY PROPERTIES | PHARMACOR INC. (CA) | 2000-10-12 | — | — | WO | disclosed |