Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | UBE2M | P61081 | 4/20 | 0.46 |
| ▸ | DCUN1D1 | Q96GG9 | 4/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5146982 | 0.75 | KDM4E (0.69) | KDM4EALDH1A1SMN1; SMN2HPGDPOLB | |
| SCHEMBL9823734 | 0.72 | KDM4E (0.69) | KDM4EALDH1A1SMN1; SMN2HPGDPOLB | |
| SCHEMBL23657551 | 0.66 | ALDH1A1 (0.83) | KDM4EALDH1A1SMN1; SMN2HPGDPOLB | |
| SCHEMBL15452766 | 0.64 | KDM4E (0.74) | KDM4EALDH1A1SMN1; SMN2HPGDPOLB | |
| SCHEMBL8943817 | 0.63 | KDM4E (0.69) | KDM4EALDH1A1SMN1; SMN2HPGDPOLB | |
| SCHEMBL5315895 | 0.61 | KDM4E (0.54) | KDM4EALDH1A1SMN1; SMN2HPGDPOLB | |
| SCHEMBL5330370 | 0.61 | ALDH1A1 (0.50) | KDM4EALDH1A1SMN1; SMN2HPGDPOLB | |
| SCHEMBL14506996 | 0.61 | KDM4E (0.52) | KDM4EALDH1A1SMN1; SMN2HPGDPOLB | |
| SCHEMBL9538953 | 0.60 | KDM4E (0.62) | KDM4EALDH1A1SMN1; SMN2HPGDPOLB | |
| SCHEMBL868954 | 0.60 | KDM4E (0.49) | KDM4EALDH1A1SMN1; SMN2HPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6369065-B1 | CEREBROVASCULAR AND CARDIOVASCULAR DISORDERS | UCB S.A. (BE) | 2002-04-09 | — | — | US | claimed |
| US-6369065-B1 | CEREBROVASCULAR AND CARDIOVASCULAR DISORDERS | UCB S.A. (BE) | 2002-04-09 | — | — | US | disclosed |