SCHEMBL8943817

SCHEMBL8943817

Oc1cc(-c2ccccc2)n2ncnc2n1

nearest known ligand 0.69

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 9/20 0.69
ALDH1A1 P00352 8/20 0.69
SMN1; SMN2 Q16637 2/20 0.69
MAPK1 P28482 2/20 0.68
MAPT P10636 2/20 0.68
HPGD P15428 3/20 0.56
LMNA P02545 2/20 0.56
GAA P10253 2/20 0.56
GLA P06280 1/20 0.56
TSHR P16473 2/20 0.51
HSD17B10 Q99714 1/20 0.51
L3MBTL1 Q9Y468 1/20 0.50
POLB P06746 2/20 0.48
EGLN2 Q96KS0 3/20 0.46
UBE2M P61081 2/20 0.42
DCUN1D1 Q96GG9 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15452766 0.81 KDM4E (0.74) KDM4EALDH1A1SMN1; SMN2MAPK1MAPT
SCHEMBL5146982 0.74 KDM4E (0.69) KDM4EALDH1A1SMN1; SMN2MAPK1MAPT
SCHEMBL7103183 0.73 ALDH1A1 (0.46) KDM4EALDH1A1SMN1; SMN2MAPK1MAPT
SCHEMBL11476738 0.73 ALDH1A1 (0.74) KDM4EALDH1A1SMN1; SMN2MAPK1MAPT
SCHEMBL868954 0.71 KDM4E (0.49) KDM4EALDH1A1SMN1; SMN2MAPK1MAPT
SCHEMBL5146977 0.70 ALDH1A1 (0.67) KDM4EALDH1A1SMN1; SMN2MAPK1MAPT
SCHEMBL10887539 0.70 ALDH1A1 (0.43) KDM4EALDH1A1SMN1; SMN2MAPK1MAPT
SCHEMBL8944124 0.70 TSHR (0.52) KDM4EALDH1A1SMN1; SMN2MAPK1MAPT
SCHEMBL23925371 0.70 KDM4E (0.48) KDM4EALDH1A1SMN1; SMN2MAPK1MAPT
SCHEMBL14367601 0.70 ALDH1A1 (0.50) KDM4EALDH1A1SMN1; SMN2MAPK1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5480716-A MULTILAYER ELEMENT WITH SUPPORT AND MAGNETIC LAYER WITH FERROMAGNETIC METALS FUJI PHOTO FILM CO., LTD. (JP) 1996-01-02 US disclosed