Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.56 |
| ▸ | CHAT | P28329 | 3/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | RXRA | P19793 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29399914 | 0.89 | RXRA (0.57) | CHATHDAC8HDAC6RXRAPTGS1 | |
| SCHEMBL4626594 | 0.89 | RXRA (0.57) | CHATHDAC8HDAC6RXRAPTGS1 | |
| SCHEMBL4626591 | 0.89 | RXRA (0.57) | CHATHDAC8HDAC6RXRAPTGS1 | |
| SCHEMBL2774767 | 0.88 | CHAT (0.68) | CHATHDAC8HDAC6PTGS1PTGS2 | |
| SCHEMBL29794070 | 0.88 | CHAT (0.68) | CHATHDAC8HDAC6PTGS1PTGS2 | |
| SCHEMBL1782982 | 0.88 | CHAT (0.68) | CHATHDAC8HDAC6PTGS1PTGS2 | |
| SCHEMBL6051064 | 0.88 | CHAT (0.68) | CHATHDAC8HDAC6PTGS1PTGS2 | |
| Benzene SCHEMBL28841289 | 0.88 | CHAT (0.68) | CHATHDAC8HDAC6PTGS1PTGS2 | |
| SCHEMBL27495890 | 0.87 | RXRA (0.55) | CHATHDAC8HDAC6RXRAPTGS1 | |
| SCHEMBL27525379 | 0.87 | RXRA (0.55) | CHATHDAC8HDAC6RXRAPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6361885-B1 | ANODES AND CATHODES FOR ELECTROLUMINESCENT DEVICE | ORGANIC DISPLAY TECHNOLOGY | 2002-03-26 | — | — | US | disclosed |
| WO-2000031208-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | ORGANIC DISPLAY TECHNOLOGY (US) | 2000-06-02 | — | — | WO | disclosed |
| US-4001130-A | DETERGENTS, SUBSTITUTED BUTADIENES | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-01-04 | — | — | US | disclosed |
| US-3940340-A | Peracylated polyamines compatible with optical brighteners as activators for inorganic peroxo compounds | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-02-24 | — | — | US | disclosed |