Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | PPARD | Q03181 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SI | P14410 | 1/20 | 0.31 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1276940 | 0.82 | PPARD (0.46) | TSHRPPARDTP53TDP1ALDH1A1 | |
| SCHEMBL16047 | 0.82 | TSHR (0.48) | TSHRPPARDTP53TDP1ALDH1A1 | |
| SCHEMBL18759661 | 0.82 | TSHR (0.48) | TSHRPPARDTP53TDP1ALDH1A1 | |
| SCHEMBL1331297 | 0.82 | TSHR (0.48) | TSHRPPARDTP53TDP1ALDH1A1 | |
| SCHEMBL6669420 | 0.80 | TSHR (0.46) | TSHRPPARDTP53TDP1ALDH1A1 | |
| SCHEMBL11663536 | 0.79 | TSHR (0.58) | TSHRPPARDTP53TDP1ALDH1A1 | |
| SCHEMBL7709968 | 0.77 | TSHR (0.36) | TSHRPPARD | |
| SCHEMBL6428821 | 0.77 | TSHR (0.43) | TSHRPPARDTP53TDP1ALDH1A1 | |
| SCHEMBL15438827 | 0.77 | NAAA (0.44) | TSHRPPARDCA12CA1CA2 | |
| SCHEMBL31218556 | 0.77 | TSHR (0.43) | TSHRPPARDTDP1ALDH1A1MGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6376548-B1 | FUNGICIDES; HERBICIDES; INSECTICIDES | ROHM AND HAAS COMPANY | 2002-04-23 | — | — | US | disclosed |
| WO-2001056358-A2 | ENHANCED PROPERTIED PESTICIDES | ROHM AND HAAS COMPANY (US) | 2001-08-09 | — | — | WO | disclosed |