Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | GABRP | O00591 | 2/20 | 0.34 |
| ▸ | GABRD | O14764 | 2/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.34 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.34 |
| ▸ | GABRE | P78334 | 2/20 | 0.34 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.34 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.34 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.34 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.34 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL609024 | 0.75 | KDM4E (0.46) | KDM4EHSD17B10HIF1AGABRPGABRD | |
| SCHEMBL23634064 | 0.74 | KDM4E (0.52) | KDM4EHSD17B10GABRPGABRDGABRA1 | |
| SCHEMBL16197373 | 0.72 | HIF1A (0.39) | HIF1ASMN1; SMN2GSTP1GSTM2CA1 | |
| SCHEMBL609195 | 0.71 | KDM4E (0.53) | KDM4EHSD17B10GABRPGABRDGABRA1 | |
| SCHEMBL19240399 | 0.70 | RAB9A (0.41) | KDM4EHSD17B10GABRPGABRDGABRA1 | |
| SCHEMBL10432941 | 0.69 | MAPT (0.49) | HIF1A | |
| SCHEMBL1496675 | 0.69 | CYP2D6 (0.40) | KDM4EHSD17B10HIF1ASMN1; SMN2 | |
| SCHEMBL11454370 | 0.69 | MAOA (0.53) | HIF1ASMN1; SMN2GSTP1GSTM2CA1 | |
| SCHEMBL6482093 | 0.69 | MAOA (0.50) | HIF1ACA1CA2CA4CA7 | |
| SCHEMBL6543393 | 0.69 | MAOA (0.50) | HIF1ACA1CA2CA4CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6362191-B1 | ANTIBIOTICS | ZENECA LTD. (GB) | 2002-03-26 | — | — | US | disclosed |
| EP-1007525-A1 | AMINOMETYL OXOOXAZOLIDINYL BENZENE DERIVATIVES | ZENECA LIMITED (GB) | 2000-06-14 | — | — | EP | disclosed |
| WO-1999011642-A1 | AMINOMETYL OXOOXAZOLIDINYL BENZENE DERIVATIVES | ZENECA LIMITED (GB) | 1999-03-11 | — | — | WO | disclosed |