Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL7710348

CC(=O)OCCCN(C)C.N

nearest known ligand 0.54

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.54
RAD52 P43351 1/20 0.51
GAA P10253 2/20 0.47
CHRM5 P08912 3/20 0.45
CHRM1 P11229 3/20 0.45
CHRM3 P20309 3/20 0.45
CHRM2 P08172 2/20 0.45
CHRM4 P08173 2/20 0.45
CHRNB2 P17787 2/20 0.45
CHRNA4 P43681 2/20 0.45
TSHR P16473 3/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
SMN1; SMN2 Q16637 2/20 0.41
PGR P06401 1/20 0.41
HTR1A P08908 1/20 0.41
TBXA2R P21731 1/20 0.41
CHRNB4 P30926 1/20 0.41
CHRNA3 P32297 1/20 0.41
CHRNA7 P36544 1/20 0.41
CHRNA10 Q9GZZ6 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26314 0.98 ALDH1A1 (0.56) ALDH1A1RAD52GAACHRM5CHRM1
Water SCHEMBL28087308 0.95 ALDH1A1 (0.54) ALDH1A1RAD52GAACHRM5CHRM1
SCHEMBL761115 0.91 ALDH1A1 (0.54) ALDH1A1RAD52GAACHRM5CHRM1
SCHEMBL31440349 0.89 ALDH1A1 (0.52) ALDH1A1RAD52GAACHRM5CHRM1
SCHEMBL34462071 0.89 ALDH1A1 (0.52) ALDH1A1RAD52GAACHRM5CHRM1
SCHEMBL31297301 0.89 ALDH1A1 (0.52) ALDH1A1RAD52GAACHRM5CHRM1
SCHEMBL8756090 0.89 ALDH1A1 (0.52) ALDH1A1RAD52GAACHRM5CHRM1
SCHEMBL31440319 0.89 ALDH1A1 (0.52) ALDH1A1RAD52GAACHRM5CHRM1
SCHEMBL31440335 0.89 ALDH1A1 (0.52) ALDH1A1RAD52GAACHRM5CHRM1
SCHEMBL31440212 0.89 ALDH1A1 (0.52) ALDH1A1RAD52GAACHRM5CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6361940-B1 IMMOBILIZATION; GENETIC ENGINEERING QIAGEN GENOMICS, INC. 2002-03-26 US disclosed