Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | ACE | P12821 | 1/20 | 0.47 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.44 |
| ▸ | STS | P08842 | 1/20 | 0.44 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.42 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.42 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4556500 | 0.88 | KMT2A (0.47) | KMT2AL3MBTL1 | |
| SCHEMBL9091685 | 0.81 | OPRM1 (0.55) | KMT2AL3MBTL1DRD2 | |
| SCHEMBL14290582 | 0.81 | OPRM1 (0.55) | KMT2AL3MBTL1DRD2 | |
| SCHEMBL6172743 | 0.80 | L3MBTL1 (0.51) | KMT2AL3MBTL1NPSR1 | |
| SCHEMBL28249801 | 0.80 | KMT2A (0.56) | KMT2AL3MBTL1ACEKCNA3STS | |
| SCHEMBL5847914 | 0.79 | BTK (0.43) | KMT2AL3MBTL1KCNA3DRD2 | |
| SCHEMBL14027716 | 0.79 | MC4R (0.42) | KMT2AL3MBTL1 | |
| SCHEMBL6128768 | 0.79 | KMT2A (0.64) | KMT2AL3MBTL1KCNA3DRD2MAOB | |
| SCHEMBL555464 | 0.79 | KMT2A (0.64) | KMT2AL3MBTL1KCNA3DRD2MAOB | |
| SCHEMBL5412662 | 0.79 | KMT2A (0.64) | KMT2AL3MBTL1KCNA3DRD2MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6369077-B1 | OSTEOPOROSIS, PERIODONTITIS, AND ARTHRITIS | SMITHKLINE BEECHAM CORPORATION | 2002-04-09 | — | — | US | disclosed |