Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | PDE2A | O00408 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.33 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.33 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | JUN | P05412 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7713982 | 0.86 | PDE2A (0.40) | ALDH1A1KDM4EPDE2ASMN1; SMN2GPR35 | |
| SCHEMBL7715451 | 0.79 | GPR35 (0.36) | ALDH1A1KDM4EPDE2ASMN1; SMN2GPR35 | |
| SCHEMBL7716338 | 0.79 | ALDH1A1 (0.38) | ALDH1A1KDM4EPDE2ASMN1; SMN2GPR35 | |
| SCHEMBL7710577 | 0.77 | GPR35 (0.37) | ALDH1A1KDM4EPDE2ASMN1; SMN2GPR35 | |
| SCHEMBL7715443 | 0.77 | GPR35 (0.34) | ALDH1A1KDM4EPDE2ASMN1; SMN2GPR35 | |
| SCHEMBL7715991 | 0.77 | PDE2A (0.35) | ALDH1A1KDM4EPDE2ASMN1; SMN2GPR35 | |
| SCHEMBL7715492 | 0.76 | CA1 (0.34) | ALDH1A1KDM4EPDE2ASMN1; SMN2GPR35 | |
| SCHEMBL9723084 | 0.75 | PDE2A (0.36) | ALDH1A1KDM4EPDE2ASMN1; SMN2GPR35 | |
| SCHEMBL7716285 | 0.74 | CA1 (0.36) | ALDH1A1KDM4EPDE2ASMN1; SMN2GPR35 | |
| SCHEMBL26623682 | 0.72 | SMN1; SMN2 (0.46) | ALDH1A1KDM4ESMN1; SMN2GPR35MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6376710-B2 | INSECTICIDES, NEMATODICIDES, MITICIDES | SUMITOMO CHEMICAL CO., LTD. (JP) | 2002-04-23 | — | — | US | disclosed |
| US-20010041740-A1 | Amidine compounds and their use as pesticides | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2001-11-15 | — | — | US | disclosed |
| EP-1138668-A2 | Amidine compounds and their use as pesticides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-10-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010041740-A1 | Amidine compounds and their use as pesticides | DDT, CNR1, PRMT1 | ALDH1A1 1367/4885KDM4E 1752/4885PDE2A 1644/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.