Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.65 |
| ▸ | RECQL | P46063 | 1/20 | 0.65 |
| ▸ | POLM | Q9NP87 | 2/20 | 0.55 |
| ▸ | POLK | Q9UBT6 | 2/20 | 0.55 |
| ▸ | POLL | Q9UGP5 | 2/20 | 0.55 |
| ▸ | POLH | Q9Y253 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2525282 | 1.00 | MEN1 (0.65) | MEN1KMT2AKDM4ERECQLPOLM | |
| SCHEMBL5664646 | 1.00 | MEN1 (0.65) | MEN1KMT2AKDM4ERECQLPOLM | |
| SCHEMBL5706154 | 0.89 | KMT2A (0.65) | MEN1KMT2AKDM4ERECQLPOLM | |
| SCHEMBL2891858 | 0.89 | MEN1 (0.50) | MEN1KMT2AKDM4ERECQLPOLM | |
| SCHEMBL28470030 | 0.88 | ALDH1A1 (0.60) | MEN1KMT2AKDM4ERECQLTSHR | |
| SCHEMBL30364316 | 0.88 | ALDH1A1 (0.60) | MEN1KMT2AKDM4ERECQLTSHR | |
| SCHEMBL28711876 | 0.88 | ALDH1A1 (0.60) | MEN1KMT2AKDM4ERECQLTSHR | |
| SCHEMBL1446713 | 0.88 | ALDH1A1 (0.60) | MEN1KMT2AKDM4ERECQLTSHR | |
| SCHEMBL5706016 | 0.87 | KDM4E (0.63) | MEN1KMT2AKDM4ERECQLPOLM | |
| SCHEMBL11122088 | 0.87 | MEN1 (0.63) | MEN1KMT2AKDM4ERECQLPOLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6368615-B1 | POLYMER OF UNSATURATED ESTER OF SALICYLIC ACID | GUTTAG ALVIN (US) | 2002-04-09 | — | — | US | disclosed |
| US-6037338-A | AND REDUCING RISK OF HEART ATTACKS | GUTTAG ALVIN (US) | 2000-03-14 | — | — | US | disclosed |
| US-5910511-A | ALTERNATIVE TO ASPIRIN WHICH HAS LESSER UNDESIRABLE SIDE EFFECTS | GUTTAG ALVIN (US) | 1999-06-08 | — | — | US | disclosed |
| US-5760261-A | ANTINFLAMMATORY AGENTS, ANTIPYRETICS, ANALGESICS; SIDE EFFECTREDUCTION | GUTTAG ALVIN (US) | 1998-06-02 | — | — | US | disclosed |