Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | RECQL | P46063 | 1/20 | 0.63 |
| ▸ | POLM | Q9NP87 | 2/20 | 0.54 |
| ▸ | POLK | Q9UBT6 | 2/20 | 0.54 |
| ▸ | POLL | Q9UGP5 | 2/20 | 0.54 |
| ▸ | POLH | Q9Y253 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.49 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.49 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7892385 | 0.96 | MEN1 (0.60) | KDM4EMEN1KMT2ARECQLPOLM | |
| SCHEMBL7209562 | 0.94 | MEN1 (0.61) | KDM4EMEN1KMT2ARECQLPOLM | |
| SCHEMBL8499422 | 0.91 | MEN1 (0.61) | KDM4EMEN1KMT2ARECQLTSHR | |
| SCHEMBL8498851 | 0.88 | TSHR (0.65) | KDM4EMEN1KMT2ARECQLTSHR | |
| SCHEMBL5664646 | 0.87 | MEN1 (0.65) | KDM4EMEN1KMT2ARECQLPOLM | |
| SCHEMBL5706154 | 0.87 | KMT2A (0.65) | KDM4EMEN1KMT2ARECQLPOLM | |
| SCHEMBL7710669 | 0.87 | MEN1 (0.65) | KDM4EMEN1KMT2ARECQLPOLM | |
| SCHEMBL2525282 | 0.87 | MEN1 (0.65) | KDM4EMEN1KMT2ARECQLPOLM | |
| SCHEMBL13425197 | 0.87 | HDAC1 (0.54) | KDM4EMEN1KMT2ARECQLTSHR | |
| SCHEMBL14723637 | 0.87 | KDM4E (0.51) | KDM4EMEN1KMT2ARECQLPOLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1412411-B1 | PROCESS FOR PREPARING POLYCARBONATE AND APPARATUS FOR PREPARING POLYCARBONATE | GEN ELECTRIC (US) | 2006-08-09 | — | — | EP | disclosed |
| EP-1412411-A2 | PROCESS FOR PREPARING POLYCARBONATE AND APPARATUS FOR PREPARING POLYCARBONATE | GENERAL ELECTRIC COMPANY (US) | 2004-04-28 | — | — | EP | disclosed |
| US-6620902-B2 | Melting aromatic dihydroxy compound, a carbonic acid diester; mixing with endcapping agent under hermetic sealing | GENERAL ELECTRIC COMPANY | 2003-09-16 | — | — | US | disclosed |
| US-20030088051-A1 | Process for preparing polycarbonate and apparatus for preparing polycarbonate | GENERAL ELECTRIC COMPANY | 2003-05-08 | — | — | US | disclosed |
| WO-2003008481-A2 | PROCESS FOR PREPARING POLYCARBONATE AND APPARATUS FOR PREPARING POLYCARBONATE | GENERAL ELECTRIC COMPANY (US) | 2003-01-30 | — | — | WO | disclosed |
| US-4692552-A | Protease inhibitors | G. D. SEARLE & CO. (US) | 1987-09-08 | — | — | US | disclosed |
| EP-0124905-B1 | PROTEASE INHIBITORS | G.D. Searle & Co. (US) | 1986-10-29 | — | — | EP | disclosed |
| US-4584397-A | Protease inhibitors | G. D. SEARLE & CO. (US) | 1986-04-22 | — | — | US | disclosed |
| US-4499295-A | Protease inhibitors | G. D. SEARLE & CO. (US) | 1985-02-12 | — | — | US | disclosed |
| EP-0124905-A1 | Protease inhibitors | G.D. Searle & Co. (US) | 1984-11-14 | — | — | EP | disclosed |