Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | ITGB1 | P05556 | 11/20 | 0.39 |
| ▸ | ITGA4 | P13612 | 11/20 | 0.39 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | RAD52 | P43351 | 1/20 | 0.37 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7716196 | 0.89 | ITGB1 (0.43) | ITGB1ITGA4 | |
| SCHEMBL7716201 | 0.89 | ITGB1 (0.43) | ITGB1ITGA4 | |
| SCHEMBL7264625 | 0.86 | ITGB1 (0.43) | ITGB1ITGA4 | |
| SCHEMBL7264618 | 0.86 | ITGB1 (0.43) | ITGB1ITGA4 | |
| SCHEMBL7710715 | 0.85 | ITGB1 (0.57) | ATMITGB1ITGA4PTGDRSLC2A1 | |
| SCHEMBL7716175 | 0.85 | P2RX3 (0.36) | ITGB1ITGA4TP53MAPT | |
| SCHEMBL7716463 | 0.83 | ITGB1 (0.39) | ATMITGB1ITGA4PTGDR | |
| SCHEMBL7710707 | 0.83 | ITGB1 (0.39) | ATMITGB1ITGA4PTGDR | |
| SCHEMBL7716466 | 0.83 | ITGB1 (0.39) | ATMITGB1ITGA4PTGDR | |
| SCHEMBL7716169 | 0.83 | ELANE (0.40) | ATMITGB1ITGA4POLBTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403608-B1 | ANTIINFLAMMATORY AND IMMUNE DISORDERS | CELLTECH R&D, LTD. (GB) | 2002-06-11 | — | — | US | disclosed |