Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 10/20 | 0.36 |
| ▸ | NPR3 | P17342 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.33 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7716179 | 0.90 | ELANE (0.40) | ELANETP53MAPTITGB1ITGA4 | |
| SCHEMBL7716169 | 0.90 | ELANE (0.40) | ELANETP53MAPTITGB1ITGA4 | |
| SCHEMBL7710696 | 0.85 | ITGB1 (0.46) | NPR3ELANENOS3NOS1NOS2 | |
| SCHEMBL7710690 | 0.85 | ATM (0.39) | TP53MAPTITGB1ITGA4 | |
| SCHEMBL7716196 | 0.84 | ITGB1 (0.43) | ITGB1ITGA4 | |
| SCHEMBL7716201 | 0.84 | ITGB1 (0.43) | ITGB1ITGA4 | |
| SCHEMBL7718440 | 0.83 | MAPT (0.34) | P2RX3NPR3ELANENOS3NOS1 | |
| SCHEMBL7718435 | 0.83 | MAPT (0.34) | P2RX3NPR3ELANENOS3NOS1 | |
| SCHEMBL7264618 | 0.80 | ITGB1 (0.43) | ITGB1ITGA4 | |
| SCHEMBL7716184 | 0.80 | MAPT (0.35) | P2RX3TP53MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403608-B1 | ANTIINFLAMMATORY AND IMMUNE DISORDERS | CELLTECH R&D, LTD. (GB) | 2002-06-11 | — | — | US | disclosed |