Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | FPR1 | P21462 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7710382 | 0.91 | PARP1 (0.40) | MEN1KMT2ASMN1; SMN2CYP3A4KDM4E | |
| SCHEMBL7095640 | 0.88 | ALDH1A1 (0.37) | MEN1KMT2ASMN1; SMN2KDM4ERAB9A | |
| SCHEMBL7091267 | 0.87 | HSD17B10 (0.33) | MEN1KMT2ASMN1; SMN2KDM4ERAB9A | |
| SCHEMBL7087725 | 0.87 | CTSS (0.41) | MEN1KMT2ASMN1; SMN2RAB9AHPGD | |
| SCHEMBL7092472 | 0.87 | HSD17B10 (0.37) | MEN1KMT2ASMN1; SMN2RAB9AHPGD | |
| SCHEMBL7704943 | 0.87 | ALDH1A1 (0.43) | MEN1KMT2ASMN1; SMN2RAB9AHPGD | |
| SCHEMBL7094044 | 0.86 | SMN1; SMN2 (0.40) | MEN1KMT2ASMN1; SMN2RAB9AHPGD | |
| SCHEMBL7092669 | 0.86 | CTSS (0.34) | MEN1KMT2ASMN1; SMN2KDM4ERAB9A | |
| SCHEMBL7711070 | 0.85 | CACNA1B (0.40) | MEN1KMT2ASMN1; SMN2RAB9AHPGD | |
| SCHEMBL7090483 | 0.85 | CTSS (0.45) | MEN1KMT2ASMN1; SMN2KDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6365736-B1 | TREATMENT OF NERVOUS SYSTEM DISORDERS, CARDIOVASCULAR DISORDERS AND FOR ACTIVITY AS NO-SYNTHASES (NOS) INHIBITORS. | SCHERING AKTIENGESELLSCHAFT (DE) | 2002-04-02 | — | — | US | disclosed |