Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 4/20 | 0.40 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.37 |
| ▸ | GALR1 | P47211 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | DHODH | Q02127 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3147248 | 0.84 | NOTUM (0.42) | S1PR1S1PR5NOTUMHSP90AA1GAA | |
| SCHEMBL27649734 | 0.75 | S1PR1 (0.49) | S1PR1S1PR5NOTUMHSP90AA1GAA | |
| Hydrogen Sulfide SCHEMBL27619443 | 0.74 | S1PR1 (0.48) | S1PR1S1PR5NOTUMHSP90AA1GAA | |
| SCHEMBL6119988 | 0.73 | NOTUM (0.41) | S1PR1S1PR5NOTUMHSP90AA1GAA | |
| Fluoride SCHEMBL27744364 | 0.73 | S1PR1 (0.47) | S1PR1S1PR5NOTUMHSP90AA1GAA | |
| SCHEMBL28534069 | 0.73 | ALDH1A1 (0.52) | S1PR1S1PR5NOTUMHSP90AA1GAA | |
| SCHEMBL59138 | 0.72 | NOTUM (0.55) | S1PR1S1PR5NOTUMHSP90AA1GAA | |
| SCHEMBL30278469 | 0.71 | CYP3A4 (0.50) | S1PR1S1PR5NOTUMHSP90AA1GAA | |
| SCHEMBL25644781 | 0.71 | ALDH1A1 (0.50) | S1PR1S1PR5NOTUMHSP90AA1GAA | |
| SCHEMBL5381085 | 0.71 | KDM1A (0.56) | S1PR1S1PR5NOTUMHSP90AA1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6358665-B1 | ONIUM SALT PRECURSOR FOR GENERATING FLUOROALKYLSULFONATE | CLARIANT INTERNATIONAL LTD. (CH) | 2002-03-19 | — | — | US | disclosed |
| EP-1033624-A1 | RADIATION-SENSITIVE COMPOSITION OF CHEMICAL AMPLIFICATION TYPE | Clariant International Ltd. (CH) | 2000-09-06 | — | — | EP | disclosed |