SCHEMBL771193

SCHEMBL771193

C=C(C)C(=O)OCC(=O)OC(=O)CCC

nearest known ligand 0.56

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.56
TSHR P16473 3/20 0.46
THRB P10828 1/20 0.43
MGAM O43451 1/20 0.31
GAA P10253 1/20 0.31
SI P14410 1/20 0.31
MGAM2 Q2M2H8 1/20 0.31
PAM P19021 2/20 0.31
CES2 O00748 1/20 0.30
CES1 P23141 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL865331 0.88 TSHR (0.50) ALDH1A1TSHRTHRBMGAMGAA
SCHEMBL766145 0.82 ALDH1A1 (0.61) ALDH1A1TSHRTHRBMGAMGAA
SCHEMBL10714365 0.81 TSHR (0.44) ALDH1A1TSHRTHRB
SCHEMBL28191221 0.80 ALDH1A1 (0.58) ALDH1A1TSHRTHRBMGAMGAA
SCHEMBL27646215 0.80 TSHR (0.47) ALDH1A1TSHRTHRBMGAMGAA
SCHEMBL428777 0.80 ALDH1A1 (0.58) ALDH1A1TSHRTHRBMGAMGAA
SCHEMBL27884437 0.80 ALDH1A1 (0.65) ALDH1A1TSHRPAMCES2CES1
SCHEMBL17240329 0.80 TSHR (0.47) ALDH1A1TSHRTHRBMGAMGAA
SCHEMBL865332 0.80 TSHR (0.47) ALDH1A1TSHRTHRBMGAMGAA
SCHEMBL28873475 0.80 ALDH1A1 (0.79) ALDH1A1TSHRCES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120070879-A1 REDUCTION OF ANTIBIOTIC ACTIVITY OR CONCENTRATION IN BIOLOGICAL SAMPLES USING MOLECULARLY IMPRINTED POLYMERS BECTON, DICKINSON AND COMPANY (US) 2012-03-22 US disclosed
WO-2010144348-A2 REDUCTION OF ANTIBIOTIC ACTIVITY OR CONCENTRATION IN BIOLOGICAL SAMPLES USING MOLECULARLY IMPRINTED POLYMERS BECTON, DICKINSON AND COMPANY (US) 2010-12-16 WO disclosed