Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.58 |
| ▸ | MAPT | P10636 | 5/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | ACHE | P22303 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6814730 | 0.87 | ALDH1A1 (0.65) | ALDH1A1MAPTMEN1KMT2AHTT | |
| SCHEMBL6815899 | 0.83 | ALDH1A1 (0.61) | ALDH1A1MAPTMEN1KMT2AHTT | |
| SCHEMBL6816343 | 0.80 | MAPT (0.68) | ALDH1A1MAPTMEN1KMT2AHTT | |
| SCHEMBL10817064 | 0.80 | SMN1; SMN2 (0.71) | ALDH1A1MAPTMEN1KMT2AHTT | |
| SCHEMBL7592685 | 0.80 | ALDH1A1 (0.60) | ALDH1A1MAPTMEN1KMT2AHTT | |
| SCHEMBL6814846 | 0.79 | ALDH1A1 (0.53) | ALDH1A1MAPTMEN1KMT2AGAA | |
| SCHEMBL7592691 | 0.79 | ALDH1A1 (0.62) | ALDH1A1MAPTMEN1KMT2AHTT | |
| SCHEMBL9659046 | 0.78 | KMT2A (0.70) | ALDH1A1MAPTMEN1KMT2AHTT | |
| SCHEMBL6815553 | 0.78 | SMN1; SMN2 (0.65) | ALDH1A1MAPTMEN1KMT2ANPC1 | |
| SCHEMBL10494904 | 0.77 | ALDH1A1 (0.65) | ALDH1A1MAPTMEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6380243-B1 | INCLUDING HUMAN CYTOMEGALOVIRUS, HERPES SIMPLEX VIRUSES, EPSTEIN-BARR VIRUS, VARICELLA-ZOSTER VIRUS, HUMAN HERPESVIRUSES- 6 AND -7, AND KAPOSI HERPESVIRUS. | AMERICAN HOME PRODUCTS CORPORATION | 2002-04-30 | — | — | US | disclosed |