Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.57 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.57 |
| ▸ | DNM2 | P50570 | 9/20 | 0.56 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | AHR | P35869 | 1/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9107176 | 0.85 | ESR1 (0.50) | ESR1ESR2DNM2ALDH1A1LMNA | |
| SCHEMBL13967286 | 0.85 | ESR1 (0.68) | ESR1ESR2DNM2ALDH1A1LMNA | |
| SCHEMBL7164892 | 0.83 | NUDT1 (0.62) | ESR1ESR2DNM2NUDT1CYP2C19 | |
| SCHEMBL7712163 | 0.81 | DNM2 (0.47) | ESR1DNM2NUDT1ALDH1A1LMNA | |
| Sulfuric Acid SCHEMBL20164450 | 0.79 | ESR1 (0.44) | ESR1ESR2DNM2ALDH1A1LMNA | |
| SCHEMBL16608745 | 0.78 | DNM2 (0.61) | ESR1ESR2DNM2ALDH1A1LMNA | |
| SCHEMBL16293225 | 0.76 | ESR1 (0.50) | ESR1ESR2DNM2ALDH1A1LMNA | |
| SCHEMBL9105998 | 0.76 | ESR1 (0.58) | ESR1ESR2DNM2ALDH1A1LMNA | |
| SCHEMBL15739197 | 0.76 | ESR1 (0.41) | ESR1ESR2DNM2ALDH1A1LMNA | |
| SCHEMBL15720241 | 0.76 | ESR1 (0.41) | ESR1ESR2DNM2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6380263-B1 | ADMINISTERING TO HUMAN EFFECTIVE TYROSINASE ACTIVITY-STIMULATING AMOUNT OF AT LEAST ONE 6-SUBSTITUTED PYRIMIDINE 3-OXIDE COMPOUND FOR PROMOTING PIGMENTATION OF THE SKIN AND/OR HAIR | SOCIETE L'OREAL (FR) | 2002-04-30 | — | — | US | disclosed |
| US-5756092-A | DRUGS OR COSMETIC MIXTURE TREATING SKIN DISORDERS, ALOPECIA | SOCIETEL'OREAL S.A. (FR) | 1998-05-26 | — | — | US | disclosed |