Acetone

Acetone

SCHEMBL7712372

CC(C)=O.O=C1CCC(=O)CC(=O)C1

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.38
CYP2A6 P11509 1/20 0.35
NOTUM Q6P988 1/20 0.30
ALDH1A1 P00352 1/20 0.30
TRIM24 O15164 1/20 0.30
TRIM33 Q9UPN9 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL118264 0.83 CYP2A6 (0.43) CYP2A6ALDH1A1TRIM24TRIM33
SCHEMBL8998614 0.79 CYP2A6 (0.41) CYP2A6ALDH1A1TRIM24TRIM33
Acetone SCHEMBL3129832 0.79
SCHEMBL9989026 0.79
SCHEMBL73117 0.79
SCHEMBL9627922 0.75
SCHEMBL8022297 0.75 TRIM24 (0.50) CYP2A6ALDH1A1TRIM24TRIM33
SCHEMBL29285366 0.75
SCHEMBL9066344 0.75 TRIM24 (0.50) CYP2A6ALDH1A1TRIM24TRIM33
SCHEMBL501836 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6361998-B1 CULTURING AN INITIAL POPULATION CONTAINING ERYTHROID PRECURSORS IN A SERUM FREE DEFINED MEDIUM ESSENTIALLY FREE OF FATTY ACIDS AND HYDROCORTISONE COMPRISING SERUM ALBUMIN, INSULIN, TRANSFERRIN, IL-3, SCF, SA AND EPO AND RECOVERING HEMOSOL INC. (CA) 2002-03-26 US disclosed
EP-1104455-A2 MEDIA AND METHODS FOR EXPANSION OF ERYTHROID STEM CELLS FOR THE PRODUCTION OF HEMOGLOBIN HEMOSOL INC. (CA) 2001-06-06 EP disclosed
WO-1999067360-A2 MEDIA AND METHODS FOR EXPANSION OF ERYTHROID STEM CELLS FOR THE PRODUCTION OF HEMOGLOBIN HEMOSOL INC. (CA) 1999-12-29 WO disclosed