Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 16/20 | 0.62 |
| ▸ | F2 | P00734 | 4/20 | 0.50 |
| ▸ | BRD4 | O60885 | 1/20 | 0.50 |
| ▸ | CCR2 | P41597 | 2/20 | 0.47 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6436996 | 0.90 | F10 (0.71) | F10F2 | |
| SCHEMBL7712483 | 0.83 | F10 (0.53) | F10BRD4CCR2NTRK1 | |
| SCHEMBL6434131 | 0.81 | F10 (0.59) | F10F2 | |
| Hydrochloric Acid SCHEMBL6434172 | 0.81 | F10 (0.85) | F10F2 | |
| SCHEMBL6437209 | 0.79 | F10 (0.59) | F10F2 | |
| SCHEMBL27513366 | 0.79 | CCR2 (0.72) | F10CCR2 | |
| SCHEMBL6433197 | 0.78 | F10 (0.68) | F10F2 | |
| SCHEMBL12585719 | 0.78 | F10 (0.70) | F10CCR2 | |
| SCHEMBL6432441 | 0.77 | F10 (0.58) | F10F2BRD4CCR2 | |
| SCHEMBL7426326 | 0.77 | NTRK1 (0.50) | F10BRD4NTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1220681-C | Indole derivatives as XA factor inhibitors | AVENTIS MEDICINES DEUTSCHLAND (DE) | 2005-09-28 | — | — | CN | disclosed |
| US-6337344-B1 | ANTICOAGULANTS AND ENZYME INHIBITORS FOR CARDIOVASCULAR DISORDERS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2002-01-08 | — | — | US | disclosed |
| CN-1283186-A | Indole derivatives as XA factor inhibitors | AWENTIS MEDICINES DEUTSCHLAND (DE) | 2001-02-07 | — | — | CN | disclosed |