Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 4/20 | 0.51 |
| ▸ | F10 | P00742 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PPID | Q08752 | 1/20 | 0.43 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.43 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18065683 | 0.95 | F2 (0.54) | F2F10SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL11862581 | 0.89 | F10 (0.47) | F2F10SMN1; SMN2MAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL27733129 | 0.86 | F10 (0.50) | F2F10SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL9075590 | 0.84 | KMT2A (0.46) | SMN1; SMN2ALDH1A1TSHRPOLBPRSS1 | |
| SCHEMBL4076046 | 0.83 | MMP12 (0.49) | SMN1; SMN2TSHRPOLB | |
| SCHEMBL1268395 | 0.82 | F10 (0.47) | F2F10SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL6526152 | 0.82 | SMN1; SMN2 (0.56) | F2F10SMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL8903673 | 0.81 | F2 (0.55) | F2F10SMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL5552886 | 0.81 | F2 (0.52) | F2F10SMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL2311407 | 0.81 | F2 (0.55) | F2F10SMN1; SMN2ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6369110-B1 | PROPHYLACTIC AGENT FOR DISEASES CAUSED BY THE ACCELERATION OF THE SODIUM/PROTON EXCHANGE TRANSPORT SYSTEM | SUMITOMO PHARMACEUTICALS COMPANY (JP) | 2002-04-09 | — | — | US | disclosed |
| EP-1083166-A1 | NOVEL SUBSTITUTED GUANIDINE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2001-03-14 | — | — | EP | disclosed |