Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MMP12 | P39900 | 3/20 | 0.43 |
| ▸ | MMP13 | P45452 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | METAP2 | P50579 | 1/20 | 0.41 |
| ▸ | METAP1 | P53582 | 1/20 | 0.41 |
| ▸ | CTSG | P08311 | 2/20 | 0.40 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP14 | P50281 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | CMA1 | P23946 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28382122 | 0.84 | ZDHHC2 (0.46) | KMT2ACNR2ELANEMEN1ALDH1A1 | |
| SCHEMBL7712798 | 0.84 | F2 (0.51) | POLBTSHRSMN1; SMN2ALDH1A1PRSS1 | |
| SCHEMBL28331219 | 0.84 | ELANE (0.43) | KMT2APOLBCYP19A1SMN1; SMN2ELANE | |
| SCHEMBL28331221 | 0.84 | ELANE (0.43) | KMT2APOLBCYP19A1SMN1; SMN2ELANE | |
| SCHEMBL4076046 | 0.82 | MMP12 (0.49) | KMT2AMMP12MMP13POLBTSHR | |
| SCHEMBL27498005 | 0.81 | KMT2A (0.49) | KMT2AMMP12MMP13METAP2METAP1 | |
| SCHEMBL5079134 | 0.79 | ZDHHC2 (0.50) | CNR2ALDH1A1PRSS1 | |
| SCHEMBL5075409 | 0.79 | ZDHHC2 (0.50) | CNR2ALDH1A1PRSS1 | |
| SCHEMBL5075436 | 0.79 | ZDHHC2 (0.50) | CNR2ALDH1A1PRSS1 | |
| SCHEMBL5076058 | 0.79 | ZDHHC2 (0.50) | CNR2ALDH1A1PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5576323-A | CENTRAL NERVOUS SYSTEM DISORDERS | ELI LILLY AND COMPANY (US) | 1996-11-19 | — | — | US | disclosed |