SCHEMBL7712882

SCHEMBL7712882

CC(C)(c1ccccc1)c1ccc2cc(O)c(C(=O)O)cc2c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 2/20 0.46
ESR2 Q92731 2/20 0.46
ALDH1A1 P00352 2/20 0.46
CYP3A4 P08684 1/20 0.46
ACMSD Q8TDX5 1/20 0.44
CNR1 P21554 2/20 0.43
CNR2 P34972 2/20 0.43
GRIN2D O15399 1/20 0.43
GRIN2A Q12879 1/20 0.43
GRIN2B Q13224 1/20 0.43
GRIN2C Q14957 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.42
MPL P40238 1/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
POLB P06746 1/20 0.40
KDM4E B2RXH2 1/20 0.40
HPGD P15428 1/20 0.40
MITF O75030 1/20 0.40
GAA P10253 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9498812 0.99 ESR1 (0.45) ESR1ESR2ALDH1A1CYP3A4ACMSD
Zinc Ion SCHEMBL9498802 0.87 ESR1 (0.42) ESR1ESR2ALDH1A1CYP3A4CNR1
SCHEMBL8645226 0.84 HSD17B10 (0.47) ALDH1A1ACMSDGRIN2DGRIN2AGRIN2B
SCHEMBL1110448 0.84 HSD17B10 (0.47) ALDH1A1ACMSDGRIN2DGRIN2AGRIN2B
SCHEMBL5885487 0.83 ALDH1A1 (0.53) ESR1ESR2ALDH1A1CYP3A4ACMSD
SCHEMBL5442998 0.83 ESR1 (0.53) ESR1ESR2ALDH1A1CYP3A4ACMSD
SCHEMBL7084800 0.81 ESR1 (0.52) ESR1ESR2ALDH1A1CYP3A4ACMSD
SCHEMBL9769854 0.79 GRIN2D (0.47) ESR1ESR2ALDH1A1CYP3A4ACMSD
SCHEMBL24895087 0.78 MPL (0.58) ALDH1A1GRIN2DGRIN2AGRIN2BGRIN2C
SCHEMBL24895077 0.78 MPL (0.58) ALDH1A1GRIN2DGRIN2AGRIN2BGRIN2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6383982-B1 DYE DEVELOPERS FOR COLORING, METAL SALICYLATE AND POLYESTER POLYOLS WITH CARBONATE OR ESTER MITSUI CHEMICALS, INC. (JP) 2002-05-07 US disclosed
US-5328884-A Salicylic acid salt,and amide or sulfonamide as developer KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1994-07-12 US disclosed
US-5250108-A Mixture of salicylic acid salt, amide and sulfonamide compounds KANZAKI PAPER MANUFACTURING CO. LTD. (JP) 1993-10-05 US disclosed
US-5164001-A Salicylic salt, acrylamide copolymer SANKO KAIHATSU KAGAKU KENKYUSHO (JP) 1992-11-17 US disclosed