SCHEMBL7713237

SCHEMBL7713237

O=C(O)COc1cccc2c1CCCC(O)(COC(=O)N(c1ccccc1)c1ccccc1)C2

nearest known ligand 0.90

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PTGIR P43119 16/20 0.90
PTGDR Q13258 3/20 0.90
PTGER1 P34995 1/20 0.90
PTGER3 P43115 1/20 0.90
RXRB P28702 3/20 0.38
RXRA P19793 2/20 0.38
RXRG P48443 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29760759 0.95 PTGIR (1.00) PTGIRPTGDRPTGER1PTGER3
SCHEMBL6612986 0.95 PTGIR (1.00) PTGIRPTGDRPTGER1PTGER3
SCHEMBL6612991 0.95 PTGIR (1.00) PTGIRPTGDRPTGER1PTGER3
SCHEMBL7778677 0.95 PTGIR (1.00) PTGIRPTGDRPTGER1PTGER3
SCHEMBL7051509 0.90 PTGIR (0.91) PTGIRPTGDRPTGER1PTGER3
SCHEMBL7050827 0.90 PTGIR (0.91) PTGIRPTGDRPTGER1PTGER3
SCHEMBL7048691 0.90 PTGIR (0.89) PTGIRPTGDRPTGER1PTGER3
SCHEMBL7050802 0.88 PTGIR (0.87) PTGIRPTGDRPTGER1PTGER3
SCHEMBL7052038 0.88 PTGIR (0.86) PTGIRPTGDRPTGER1PTGER3
SCHEMBL7052364 0.86 PTGIR (0.82) PTGIRPTGDRPTGER1PTGER3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6384072-B1 CARBAMYL SUBSTITUTED COMPOUNDS WITH ETHER GROUPS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2002-05-07 US disclosed