SCHEMBL7713263

SCHEMBL7713263

CCCCNC1CC(C)(C)N(C)C(C)(C)C1c1nc(NCCO)nc(C2C(NCCCC)CC(C)(C)N(C)C2(C)C)n1

nearest known ligand 0.39

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
SLC29A1 Q99808 1/20 0.39
FLT3 P36888 2/20 0.36
TYRO3 Q06418 2/20 0.36
MERTK Q12866 2/20 0.36
GAS6 Q14393 2/20 0.36
KMT2A Q03164 1/20 0.36
GBA1 P04062 1/20 0.32
CDK1 P06493 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL39771 0.83 FLT3 (0.31) FLT3TYRO3MERTKGAS6
SCHEMBL4593354 0.76 FLT3 (0.31) FLT3TYRO3MERTKGAS6
SCHEMBL5650386 0.71
SCHEMBL6725345 0.67
SCHEMBL2783134 0.65 SLC29A1 (0.73) SLC29A1FLT3TYRO3MERTKGAS6
SCHEMBL9913748 0.65 SLC29A1 (0.73) SLC29A1FLT3TYRO3MERTKGAS6
SCHEMBL870341 0.61 GNAI3 (0.37) FLT3TYRO3MERTKGAS6GBA1
SCHEMBL8386905 0.60 FUCA1 (0.37) GBA1
SCHEMBL13531453 0.60 FLT3 (0.39) SLC29A1FLT3TYRO3MERTKGAS6
SCHEMBL13246429 0.59 FLT3 (0.36) FLT3TYRO3MERTKGAS6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6365652-B2 AMIDO OR CARBAMATE SUBSTITUTED TRISARYL-1,3,5-TRIAZINES USED AS ACTINIC RADIATION STABILIZER BY INCORPORATING THE ABOVE COMPOUND INTO THE ORGANIC POLYMER BY CHEMICAL BONDING CIBA SPECIALTY CHEMICALS CORPORATION 2002-04-02 US disclosed
US-20010037022-A1 Trisaryl-1,3,5-triazine ultraviolet light absorbers GUPTA RAM BABOO (US) 2001-11-01 US disclosed
US-6265576-B1 STABILIZERS CIBA SPECIALTY CHEMICALS CORPORATION 2001-07-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010037022-A1 Trisaryl-1,3,5-triazine ultraviolet light absorbers CRYZ, ERCC5, TELO2 SLC29A1 2162/4885FLT3 2022/4885TYRO3 332/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.