Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 7/20 | 0.56 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | PPARA | Q07869 | 6/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CTSC | P53634 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7713441 | 0.86 | PPARG (0.71) | PPARGEPHX2KMT2AMEN1PPARA | |
| SCHEMBL7713444 | 0.86 | PPARG (0.71) | PPARGEPHX2KMT2AMEN1PPARA | |
| Hydrochloric Acid SCHEMBL9239573 | 0.84 | PPARG (0.69) | PPARGEPHX2KMT2AMEN1PPARA | |
| SCHEMBL620307 | 0.84 | CYP1A2 (0.64) | PPARGEPHX2PPARACYP1A2PPARD | |
| SCHEMBL7333189 | 0.83 | PPARG (0.49) | PPARGEPHX2PPARACYP1A2PPARD | |
| SCHEMBL8663107 | 0.82 | PPARG (0.55) | PPARGEPHX2KMT2AMEN1PPARA | |
| SCHEMBL4663230 | 0.81 | CYP1A2 (0.65) | PPARGEPHX2KMT2APPARACYP1A2 | |
| SCHEMBL10356762 | 0.80 | LDHA (0.60) | PPARGEPHX2KMT2APPARAPPARD | |
| Acetamide SCHEMBL7277641 | 0.78 | CYP1A2 (0.56) | PPARGEPHX2PPARACYP1A2PPARD | |
| SCHEMBL7330810 | 0.78 | PPARG (0.60) | PPARGEPHX2PPARACYP1A2PPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0407588-B1 | PROCESS FOR PRODUCING 2-OXO-3-AROMATIC CARBOXYLIC ACID DERIVATIVES | SAGAMI CHEM RES (JP) | 1993-12-08 | — | — | EP | disclosed |
| US-5028738-A | Process for producing 2-oxo-3-aromatic carboxylic acid derivatives | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1991-07-02 | — | — | US | disclosed |
| EP-0407588-A1 | PROCESS FOR PRODUCING 2-OXO-3-AROMATIC CARBOXYLIC ACID DERIVATIVES | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1991-01-16 | — | — | EP | disclosed |