Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.80 |
| ▸ | NPC1 | O15118 | 7/20 | 0.80 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.80 |
| ▸ | HTT | P42858 | 4/20 | 0.80 |
| ▸ | MAPT | P10636 | 4/20 | 0.80 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.80 |
| ▸ | LMNA | P02545 | 2/20 | 0.80 |
| ▸ | MEN1 | O00255 | 7/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.64 |
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.57 |
| ▸ | PIM1 | P11309 | 1/20 | 0.57 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.57 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.57 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.57 |
| ▸ | FLT3 | P36888 | 1/20 | 0.57 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.57 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13235178 | 0.89 | RAB9A (1.00) | RAB9ANPC1SMN1; SMN2HTTMAPT | |
| SCHEMBL1721544 | 0.81 | SMN1; SMN2 (0.65) | RAB9ANPC1SMN1; SMN2HTTMAPT | |
| SCHEMBL16566586 | 0.81 | ALDH1A1 (0.55) | RAB9ANPC1SMN1; SMN2HTTMAPT | |
| SCHEMBL4106734 | 0.80 | RAB9A (0.68) | RAB9ANPC1SMN1; SMN2HTTMAPT | |
| SCHEMBL27092749 | 0.80 | SMN1; SMN2 (0.68) | RAB9ANPC1SMN1; SMN2HTTMAPT | |
| SCHEMBL1463313 | 0.79 | SMN1; SMN2 (0.62) | RAB9ANPC1SMN1; SMN2HTTMAPT | |
| SCHEMBL30117873 | 0.79 | RAB9A (0.79) | RAB9ANPC1SMN1; SMN2HTTMAPT | |
| SCHEMBL3096372 | 0.79 | RAB9A (0.79) | RAB9ANPC1SMN1; SMN2HTTMAPT | |
| SCHEMBL7736903 | 0.79 | NPC1 (0.63) | RAB9ANPC1SMN1; SMN2HTTMAPT | |
| SCHEMBL21810514 | 0.78 | SMN1; SMN2 (0.81) | RAB9ANPC1SMN1; SMN2HTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105360285-A | Fresh keeping agent and method for preventing picked wax apple fruits from becoming flocculent and soft | UNIV JIMEI | 2016-03-02 | — | — | CN | disclosed |
| US-20100173917-A1 | UREA DERIVATIVES AS ABL MODULATORS | AMBIT BIOSCIENCES CORPORATION | 2010-07-08 | — | — | US | disclosed |
| US-20100173917-A1 | UREA DERIVATIVES AS ABL MODULATORS | AMBIT BIOSCIENCES CORPORATION | 2010-07-08 | — | — | US | disclosed |
| US-7750160-B2 | Isoxazolyl urea derivatives as kinase modulators | AMBIT BIOSCIENCES CORPORATION (US) | 2010-07-06 | — | — | US | disclosed |
| US-7750160-B2 | Isoxazolyl urea derivatives as kinase modulators | AMBIT BIOSCIENCES CORPORATION (US) | 2010-07-06 | — | — | US | disclosed |
| US-RE37664-E1 | Use of derivatives of N-phenl-3,4,5,6-tetrahydrophthalimide for the desiccation and abscission of plant organs | BASF AKTIENGESSELLSCHAFT (DE) | 2002-04-16 | — | — | US | disclosed |
| US-5171352-A | Applying phenylsulfonylurea compound before harvesting bolls | BASF AKTIENGESELLSCHAFT (DE) | 1992-12-15 | — | — | US | disclosed |
| US-5087282-A | Sulfonylura agents for defoliating cotton | BASF AKTIENGESELLSCHAFT (DE) | 1992-02-11 | — | — | US | disclosed |
| US-5045105-A | Use of derivatives of n-phenyl-3,4,5,6-tetrahydrophthalimide for the desiccation and abscission of plant organs | BASF AKTIENGESELLSCHAFT (DE) | 1991-09-03 | — | — | US | disclosed |
| US-4144341-A | ANTIPYRETICS, ANALGESICS AND ANTIINFLAMMATORY AGENTS | MERCK & CO., INC. (US) | 1979-03-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100173917-A1 | UREA DERIVATIVES AS ABL MODULATORS | ABL1, ABL2, BCR | RAB9A 1325/4885NPC1 1569/4885SMN1; SMN2 3974/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.