Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 12/20 | 0.38 |
| ▸ | CCKBR | P32239 | 2/20 | 0.33 |
| ▸ | XIAP | P98170 | 3/20 | 0.32 |
| ▸ | HTR5A | P47898 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7714138 | 1.00 | SIRT2 (0.38) | SIRT2CCKBRXIAPHTR5A | |
| SCHEMBL7717495 | 0.85 | SIRT2 (0.36) | SIRT2CCKBR | |
| SCHEMBL7717491 | 0.85 | SIRT2 (0.36) | SIRT2CCKBR | |
| SCHEMBL7714044 | 0.78 | SIRT2 (0.34) | SIRT2 | |
| SCHEMBL7714045 | 0.78 | SIRT2 (0.34) | SIRT2 | |
| SCHEMBL7718980 | 0.72 | SIRT2 (0.34) | SIRT2 | |
| SCHEMBL7718984 | 0.72 | SIRT2 (0.34) | SIRT2 | |
| SCHEMBL7714104 | 0.70 | SIRT2 (0.33) | SIRT2 | |
| SCHEMBL7714107 | 0.70 | SIRT2 (0.33) | SIRT2 | |
| SCHEMBL27154343 | 0.69 | HDAC1 (0.38) | SIRT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6441017-B1 | Inhibitors of prenyl-protein transferase | MERCK & CO., INC. | 2002-08-27 | — | — | US | disclosed |