Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 8/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7718984 | 1.00 | SIRT2 (0.34) | SIRT2ROCK2GRM5GRM1 | |
| SCHEMBL7717495 | 0.88 | SIRT2 (0.36) | SIRT2GRM5GRM1 | |
| SCHEMBL7717491 | 0.88 | SIRT2 (0.36) | SIRT2GRM5GRM1 | |
| SCHEMBL7714044 | 0.87 | SIRT2 (0.34) | SIRT2 | |
| SCHEMBL7714045 | 0.87 | SIRT2 (0.34) | SIRT2 | |
| SCHEMBL7717539 | 0.82 | SIRT2 (0.35) | SIRT2 | |
| SCHEMBL7717537 | 0.82 | SIRT2 (0.35) | SIRT2 | |
| SCHEMBL7169453 | 0.82 | SIRT2 (0.34) | SIRT2 | |
| SCHEMBL7714104 | 0.81 | SIRT2 (0.33) | SIRT2 | |
| SCHEMBL7714107 | 0.81 | SIRT2 (0.33) | SIRT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6441017-B1 | Inhibitors of prenyl-protein transferase | MERCK & CO., INC. | 2002-08-27 | — | — | US | disclosed |