Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 13/20 | 0.36 |
| ▸ | NMBR | P28336 | 1/20 | 0.31 |
| ▸ | CCKBR | P32239 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GRM5 | P41594 | 1/20 | 0.30 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7717491 | 1.00 | SIRT2 (0.36) | SIRT2NMBRCCKBRKDM4EALDH1A1 | |
| SCHEMBL7714045 | 0.93 | SIRT2 (0.34) | SIRT2 | |
| SCHEMBL7714044 | 0.93 | SIRT2 (0.34) | SIRT2 | |
| SCHEMBL7718980 | 0.88 | SIRT2 (0.34) | SIRT2GRM5GRM1 | |
| SCHEMBL7718984 | 0.88 | SIRT2 (0.34) | SIRT2GRM5GRM1 | |
| SCHEMBL7714107 | 0.86 | SIRT2 (0.33) | SIRT2 | |
| SCHEMBL7714104 | 0.86 | SIRT2 (0.33) | SIRT2 | |
| SCHEMBL7714134 | 0.85 | SIRT2 (0.38) | SIRT2CCKBR | |
| SCHEMBL7714138 | 0.85 | SIRT2 (0.38) | SIRT2CCKBR | |
| SCHEMBL7717537 | 0.81 | SIRT2 (0.35) | SIRT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6441017-B1 | Inhibitors of prenyl-protein transferase | MERCK & CO., INC. | 2002-08-27 | — | — | US | disclosed |