SCHEMBL7714263

SCHEMBL7714263

CC(C)(C)[Si](C)(C)Oc1ccc(F)cc1I

nearest known ligand 0.34

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALOX5AP P20292 2/20 0.34
FEN1 P39748 2/20 0.34
TRPA1 O75762 3/20 0.33
CA12 O43570 4/20 0.33
CA1 P00915 4/20 0.33
CA9 Q16790 4/20 0.33
DRD2 P14416 1/20 0.32
ALPL P05186 1/20 0.30
HTR2A P28223 2/20 0.30
HTR2C P28335 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL856992 0.82 TRPA1 (0.41) ALOX5APFEN1TRPA1
SCHEMBL1178694 0.81 SLC6A4 (0.38) ALOX5APFEN1CA12CA1CA9
SCHEMBL1056366 0.80 ALOX5AP (0.36) ALOX5APFEN1TRPA1CA12CA1
SCHEMBL17337274 0.79 DRD2 (0.44) TRPA1DRD2ALPLHTR2AHTR2C
SCHEMBL9097154 0.79 SLC6A4 (0.40) ALOX5APFEN1TRPA1HTR2AHTR2C
SCHEMBL1094866 0.79 S1PR4 (0.34) CA12CA1CA9DRD2ALPL
SCHEMBL14573872 0.77 FFAR1 (0.38) ALOX5APFEN1CA12CA1CA9
SCHEMBL1178457 0.77 DRD2 (0.38) ALOX5APFEN1DRD2HTR2AHTR2C
SCHEMBL19354829 0.76 SLC6A4 (0.36) ALOX5APFEN1CA12CA1CA9
SCHEMBL10185346 0.76 ALOX5AP (0.34) ALOX5APFEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6369279-B1 STYRENE WITH ETHER OR FLUORINE GROUPS FOR POLYMERS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2002-04-09 US disclosed
US-6333436-B1 Styrene derivatives SHIN-ETSU CHEMICAL CO., LTD. (JP) 2001-12-25 US disclosed