SCHEMBL7714448

SCHEMBL7714448

C=C(C(=O)O)C(CC)[SiH](OCCCC)OCCCC

nearest known ligand 0.41

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.33
ALDH1A1 P00352 1/20 0.33
HPGD P15428 1/20 0.33
TP53 P04637 1/20 0.32
HCAR2 Q8TDS4 1/20 0.32
ATM Q13315 1/20 0.32
CA2 P00918 1/20 0.32
MAPK1 P28482 1/20 0.32
PLA2G4B P0C869 3/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8162307 0.82
SCHEMBL4090088 0.81 TSHR (0.32) TSHRALDH1A1HPGDTP53HCAR2
SCHEMBL7516193 0.77
SCHEMBL8156560 0.74
SCHEMBL2690161 0.70 CA2 (0.38) TSHRALDH1A1HPGDTP53HCAR2
SCHEMBL28920703 0.69 ALDH1A1 (0.39) TSHRALDH1A1HPGDTP53HCAR2
SCHEMBL2790775 0.69 CYP3A4 (0.41) TSHRALDH1A1HPGD
SCHEMBL125751 0.68 ALDH1A1 (0.38) TSHRALDH1A1HPGDTP53HCAR2
SCHEMBL8161066 0.68 ALDH1A1 (0.35) TSHRALDH1A1HPGDTP53HCAR2
SCHEMBL144126 0.68 TSHR (0.44) TSHRALDH1A1HPGDATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6376615-B1 USING FREE RADICALS CENTRO DE INVESTIGACION EN QUIMICA APLICADA (MX) 2002-04-23 US claimed
EP-0791016-B1 POLYMER SYNTHESIS DU PONT (US) 2000-07-12 EP claimed
US-11566087-B2 Method for producing statistical copolymer containing chloroprene monomer unit and unsaturated nitrile monomer unit, statistical copolymer, latex and use of same DENKA COMPANY LIMITED (JP) 2023-01-31 US disclosed
EP-3636675-B1 METHOD FOR PRODUCING STATISTICAL COPOLYMER CONTAINING CHLOROPRENE MONOMER UNIT AND UNSATURATED NITRILE MONOMER UNIT, STATISTICAL COPOLYMER, LATEX AND USE OF SAME DENKA COMPANY LTD (JP) 2021-10-27 EP disclosed
US-20200199260-A1 METHOD FOR PRODUCING STATISTICAL COPOLYMER CONTAINING CHLOROPRENE MONOMER UNIT AND UNSATURATED NITRILE MONOMER UNIT, STATISTICAL COPOLYMER, LATEX AND USE OF SAME DENKA COMPANY LIMITED (JP) 2020-06-25 US disclosed
EP-3636675-A1 METHOD FOR PRODUCING STATISTICAL COPOLYMER CONTAINING CHLOROPRENE MONOMER UNIT AND UNSATURATED NITRILE MONOMER UNIT, STATISTICAL COPOLYMER, LATEX AND USE OF SAME Denka Company Limited (JP) 2020-04-15 EP disclosed
US-6376615-B1 USING FREE RADICALS CENTRO DE INVESTIGACION EN QUIMICA APLICADA (MX) 2002-04-23 US disclosed