⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL85702 | 0.74 | — | — | |
| SCHEMBL3086996 | 0.74 | — | — | |
| SCHEMBL12464926 | 0.72 | — | — | |
| Hydrochloric Acid SCHEMBL8326641 | 0.72 | — | — | |
| SCHEMBL3193395 | 0.71 | — | — | |
| SCHEMBL1101973 | 0.71 | — | — | |
| SCHEMBL2918635 | 0.70 | — | — | |
| Formaldehyde SCHEMBL27624003 | 0.70 | TOP2A (0.44) | — | |
| SCHEMBL8029443 | 0.69 | ALOX5 (0.41) | — | |
| SCHEMBL12534280 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2234615-A1 | 4-IMIDAZOLIDINONES AS KV1.5 POTASSIUM CHANNEL INHIBITORS | Wyeth LLC (US) | 2010-10-06 | — | — | EP | claimed |
| WO-2009079624-A1 | 4-IMIDAZOLIDINONES AS KV1.5 POTASSIUM CHANNEL INHIBITORS | WYETH (US) | 2009-06-25 | — | — | WO | claimed |
| CN-114409680-B | PPAR agonists and uses thereof | 上海怡立舍生物技术有限公司 | 2023-11-21 | — | — | CN | disclosed |
| US-20230322692-A1 | COMPOUND AS PPAR AGONIST AND APPLICATION THEREOF | USA Elixiria Biotech Inc. (US) | 2023-10-12 | — | — | US | disclosed |
| US-11691953-B2 | Compound as PPAR agonist and application thereof | USA Elixiria Biotech Inc. | 2023-07-04 | — | — | US | disclosed |
| US-11691953-B2 | Compound as PPAR agonist and application thereof | USA Elixiria Biotech Inc. | 2023-07-04 | — | — | US | disclosed |
| CN-108250058-B | PPAR agonists and their use in the treatment of Alzheimer's disease and other diseases | 上海怡立舍生物技术有限公司 | 2022-02-11 | — | — | CN | disclosed |
| US-20200331868-A1 | COMPOUND AS PPAR AGONIST AND APPLICATION THEREOF | USA Elixiria Biotech Inc. | 2020-10-22 | — | — | US | disclosed |
| WO-2020140053-A1 | CYCLIN-DEPENDENT KINASE INHIBITORS | SPV THERAPEUTICS INC. (US) | 2020-07-02 | — | — | WO | disclosed |
| WO-2020140052-A1 | CYCLIN-DEPENDENT KINASE INHIBITORS | SPV THERAPEUTICS INC. (US) | 2020-07-02 | — | — | WO | disclosed |
| WO-2019141229-A1 | COMPOUND AS PPAR AGONIST AND APPLICATION THEREOF | 上海怡立舍生物技术有限公司 | 2019-07-25 | — | — | WO | disclosed |
| US-7160912-B2 | Heterocyclic compounds having antibacterial activity: process for their preparation and pharmaceutical compositions containing them | DR.REDDY'S LABORATORIES LTD. (IN) | 2007-01-09 | — | — | US | disclosed |
| US-20070004712-A1 | Salts of novel heterocyclic compounds having antibacterial activity | DR. REDDY'S LABORATORIES LTD. (IN) | 2007-01-04 | — | — | US | disclosed |
| US-20070004712-A1 | Salts of novel heterocyclic compounds having antibacterial activity | DR. REDDY'S LABORATORIES LTD. (IN) | 2007-01-04 | — | — | US | disclosed |
| US-7008533-B2 | Macrocyclic antibiotics as separation agents | CURATORS OF THE UNIVERSITY OF MISSOURI (US) | 2006-03-07 | — | — | US | disclosed |
| US-6669842-B1 | Crystallization, precipitation, filtration, electrophoresis, and chromatography using ansamacrolides, macrolides, macrocyclic peptides, or polyenes; resolution | CURATORS OF THE UNIVERSITY OF MISSOURI | 2003-12-30 | — | — | US | disclosed |
| EP-0748247-A4 | MACROCYCLIC ANTIBIOTICS AS SEPARATION AGENTS | UNIV MISSOURI (US) | 1998-05-06 | — | — | EP | disclosed |
| EP-0748247-A1 | MACROCYCLIC ANTIBIOTICS AS SEPARATION AGENTS | THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) | 1996-12-18 | — | — | EP | disclosed |
| WO-1995022390-A1 | MACROCYCLIC ANTIBIOTICS AS SEPARATION AGENTS | CURATORS OF THE UNIVERSITY OF MISSOURI (US) | 1995-08-24 | — | — | WO | disclosed |
| US-4845233-A | TOPICAL PENETRATION ENHANCER FOR PHYSIOLOGICALLY ACTIVE AGENTS | IPRX, INC. (US) | 1989-07-04 | — | — | US | disclosed |