Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | GNAO1 | P09471 | 5/20 | 0.38 |
| ▸ | GNAI3 | P08754 | 4/20 | 0.38 |
| ▸ | GNAI1 | P63096 | 4/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.37 |
| ▸ | MGLL | Q99685 | 3/20 | 0.37 |
| ▸ | FAAH | O00519 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | G6PD | P11413 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL974631 | 0.81 | THRB (0.51) | ALOX5GNAO1GNAI3GNAI1THRB | |
| SCHEMBL20376275 | 0.81 | ALOX5 (0.46) | ALOX5ALDH1A1GNAO1GNAI3GNAI1 | |
| SCHEMBL6560582 | 0.80 | ALOX5 (0.49) | ALOX5ALDH1A1GNAO1GNAI3GNAI1 | |
| SCHEMBL18634073 | 0.80 | THRB (0.53) | ALOX5GNAO1GNAI3GNAI1THRB | |
| SCHEMBL11023978 | 0.80 | ALDH1A1 (0.47) | ALOX5ALDH1A1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL12464926 | 0.77 | — | — | |
| SCHEMBL9029619 | 0.76 | THRB (0.49) | ALDH1A1FAAHTHRBHPGD | |
| Propene SCHEMBL4084262 | 0.75 | THRB (0.47) | ALOX5GNAO1GNAI3GNAI1THRB | |
| Hydrochloric Acid SCHEMBL9029064 | 0.74 | THRB (0.48) | ALDH1A1GNAO1GNAI3GNAI1THRB | |
| SCHEMBL270149 | 0.74 | KMT2A (0.57) | ALDH1A1THRBGAATP53HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3072774-B2 | — | — | 2000-08-07 | — | — | JP | claimed |
| EP-0513239-A4 | N,N'-DIHALOIMIDAZOLIDIN-4-ONES | — | 1993-03-10 | — | — | EP | claimed |
| EP-0513239-A1 | N,N'-DIHALOIMIDAZOLIDIN-4-ONES | AUBURN UNIVERSITY (US) | 1992-11-19 | — | — | EP | claimed |
| US-5126057-A | Stabilizers against solar radiation | AUBURN RESEARCH FOUNDATION (US) | 1992-06-30 | — | — | US | claimed |
| US-5057612-A | Stable, noncorrosive bicoide, disinfectant | AUBURN RESEARCH FOUNDATION (US) | 1991-10-15 | — | — | US | claimed |
| WO-1991010623-A1 | N,N'-DIHALOIMIDAZOLIDIN-4-ONES | AUBURN UNIVERSITY (US) | 1991-07-25 | — | — | WO | claimed |