Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOX1 | Q9Y5S8 | 3/20 | 0.52 |
| ▸ | TP53 | P04637 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | ROS1 | P08922 | 1/20 | 0.45 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.45 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.45 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.45 |
| ▸ | TGM2 | P21980 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.45 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.45 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.45 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25666664 | 0.94 | TP53 (0.50) | NOX1TP53SMN1; SMN2POLBBCHE | |
| SCHEMBL2113682 | 0.82 | L3MBTL1 (0.68) | NOX1TP53SMN1; SMN2POLBBCHE | |
| SCHEMBL7710864 | 0.82 | L3MBTL1 (0.68) | NOX1TP53SMN1; SMN2POLBBCHE | |
| SCHEMBL17085854 | 0.79 | TP53 (0.58) | NOX1TP53SMN1; SMN2POLBMAPT | |
| SCHEMBL29441735 | 0.79 | TP53 (0.58) | NOX1TP53SMN1; SMN2POLBMAPT | |
| SCHEMBL3190862 | 0.79 | L3MBTL1 (0.68) | TP53SMN1; SMN2POLBMAPTROS1 | |
| SCHEMBL31098239 | 0.79 | L3MBTL1 (0.68) | NOX1TP53SMN1; SMN2POLBBCHE | |
| SCHEMBL11505467 | 0.78 | NOX1 (0.51) | NOX1TP53SMN1; SMN2POLBBCHE | |
| SCHEMBL24223773 | 0.77 | BCHE (0.44) | NOX1BCHEACHECES1MAPT | |
| SCHEMBL29355916 | 0.76 | HPGD (0.51) | NOX1TP53SMN1; SMN2POLBBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011121602-A1 | PROCESS FOR PREPARATION OF DIBENZOTHIAZEPINONE COMPOUNDS | HIKAL LIMITED (IN) | 2011-10-06 | — | — | WO | disclosed |