Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.68 |
| ▸ | BCHE | P06276 | 2/20 | 0.66 |
| ▸ | ACHE | P22303 | 2/20 | 0.66 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.66 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2113682 | 0.88 | L3MBTL1 (0.68) | L3MBTL1BCHEACHENOX1CHEK1 | |
| SCHEMBL25666664 | 0.82 | TP53 (0.50) | L3MBTL1BCHEACHENOX1CHEK1 | |
| SCHEMBL8988 | 0.81 | L3MBTL1 (1.00) | L3MBTL1BCHEACHENOX1HPGD | |
| SCHEMBL8878671 | 0.81 | L3MBTL1 (0.68) | L3MBTL1BCHEACHENOX1HPGD | |
| SCHEMBL1567426 | 0.81 | L3MBTL1 (0.68) | L3MBTL1BCHEACHENOX1HPGD | |
| SCHEMBL7710864 | 0.81 | L3MBTL1 (0.68) | L3MBTL1BCHEACHENOX1HPGD | |
| SCHEMBL236458 | 0.80 | NOX1 (1.00) | L3MBTL1BCHEACHENOX1MAPT | |
| SCHEMBL29384266 | 0.80 | NOX1 (1.00) | L3MBTL1BCHEACHENOX1MAPT | |
| SCHEMBL11392691 | 0.80 | L3MBTL1 (0.60) | L3MBTL1BCHEACHENOX1HPGD | |
| SCHEMBL24223773 | 0.80 | BCHE (0.44) | L3MBTL1BCHEACHENOX1CHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4428132-A1 | SLACK-ACTIVATING COMPOUNDS AND THEIR MEDICAL USE | Johann-Wolfgang-Goethe-Universität Frankfurt am Main (DE) | 2024-09-11 | — | — | EP | disclosed |