Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | KIF11 | P52732 | 9/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3118068 | 0.86 | MAPK1 (0.42) | ALDH1A1CES1 | |
| SCHEMBL7709329 | 0.81 | KIF11 (0.41) | KIF11NPC1RAB9AALDH1A1LMNA | |
| SCHEMBL11854971 | 0.81 | KIF11 (0.41) | KIF11NPC1RAB9AALDH1A1LMNA | |
| SCHEMBL9489746 | 0.81 | MEN1 (0.32) | KIF11KCNH2 | |
| SCHEMBL9474605 | 0.79 | ESR1 (0.53) | CA4KIF11LTA4HCA12CA1 | |
| SCHEMBL1286989 | 0.76 | CA4 (0.59) | CA4KIF11KCNH2LTA4HNPC1 | |
| SCHEMBL8858901 | 0.76 | CA4 (0.59) | CA4KIF11KCNH2LTA4HNPC1 | |
| SCHEMBL8648265 | 0.76 | CA4 (0.59) | CA4KIF11KCNH2LTA4HNPC1 | |
| SCHEMBL14856630 | 0.76 | CA4 (0.59) | CA4KIF11KCNH2LTA4HNPC1 | |
| SCHEMBL5051055 | 0.76 | CA4 (0.59) | CA4KIF11KCNH2LTA4HNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6376615-B1 | USING FREE RADICALS | CENTRO DE INVESTIGACION EN QUIMICA APLICADA (MX) | 2002-04-23 | — | — | US | claimed |