Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 10/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.37 |
| ▸ | RELA | Q04206 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11854971 | 1.00 | KIF11 (0.41) | KIF11TSHRLMNAALOX12ACHE | |
| SCHEMBL11867289 | 0.92 | TSHR (0.44) | TSHRACHEHPGDNPC1RAB9A | |
| SCHEMBL3118068 | 0.89 | MAPK1 (0.42) | TSHRMAPK1ALDH1A1 | |
| SCHEMBL9474605 | 0.82 | ESR1 (0.53) | KIF11TSHRLMNAHPGDMAPK1 | |
| SCHEMBL7714530 | 0.81 | CA4 (0.46) | KIF11LMNANPC1RAB9AALDH1A1 | |
| SCHEMBL9489746 | 0.77 | MEN1 (0.32) | KIF11SMN1; SMN2MEN1KMT2AMAPK1 | |
| SCHEMBL21823972 | 0.76 | MAPK1 (0.40) | HPGDSMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL17894193 | 0.74 | NR1H2 (0.38) | KIF11TSHRMAPK1ALDH1A1 | |
| SCHEMBL17114507 | 0.74 | NR1H2 (0.38) | KIF11TSHRHPGDSMN1; SMN2NPC1 | |
| SCHEMBL7714437 | 0.73 | KCNN4 (0.42) | KIF11TSHRACHEMAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6376615-B1 | USING FREE RADICALS | CENTRO DE INVESTIGACION EN QUIMICA APLICADA (MX) | 2002-04-23 | — | — | US | claimed |
| US-6376615-B1 | USING FREE RADICALS | CENTRO DE INVESTIGACION EN QUIMICA APLICADA (MX) | 2002-04-23 | — | — | US | disclosed |