Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I3 | Q14994 | 12/20 | 0.59 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.56 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.56 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.56 |
| ▸ | FRK | P42685 | 1/20 | 0.56 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.56 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.56 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.56 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.56 |
| ▸ | GSK3B | P49841 | 1/20 | 0.56 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.56 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.56 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.56 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.56 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.56 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.56 |
| ▸ | MAP3K20 | Q9NYL2 | 1/20 | 0.56 |
| ▸ | CSNK1G3 | Q9Y6M4 | 1/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7851176 | 0.77 | PTGS2 (0.76) | NR1I3PRKD3MAP4K4FGFR1FRK | |
| SCHEMBL22615059 | 0.77 | NR1I3 (0.53) | NR1I3GAAMAPT | |
| SCHEMBL1691378 | 0.76 | NR1I3 (0.62) | NR1I3GAAMAPT | |
| SCHEMBL7714593 | 0.76 | PTGS2 (0.55) | NR1I3PTGS2GAAMAPT | |
| SCHEMBL22633856 | 0.76 | NR1I3 (0.60) | NR1I3 | |
| SCHEMBL7712248 | 0.76 | PTGS2 (0.55) | NR1I3MAP4K4MINK1PTGS2GAA | |
| SCHEMBL22633854 | 0.76 | NR1I3 (0.60) | NR1I3 | |
| SCHEMBL2553052 | 0.75 | NR1I3 (0.61) | NR1I3GAAMAPT | |
| SCHEMBL22633810 | 0.75 | NR1I3 (1.00) | NR1I3 | |
| SCHEMBL22614966 | 0.74 | NR1I3 (1.00) | NR1I3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011132048-A1 | HETEROARYL COMPOUNDS AS PDE10A INHIBITORS | GLENMARK PHARMACEUTICAL S.A. (CH) | 2011-10-27 | — | — | WO | disclosed |