Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | GABRP | O00591 | 1/20 | 0.39 |
| ▸ | GABRD | O14764 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.39 |
| ▸ | GABRE | P78334 | 1/20 | 0.39 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.39 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.39 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.39 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | BLM | P54132 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19747000 | 0.92 | MAPT (0.43) | TSHRGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL5655529 | 0.84 | MEN1 (0.33) | TSHRLMNABLMMAPTKDM4E | |
| SCHEMBL29816130 | 0.84 | MAOA (0.35) | TSHRGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL980578 | 0.84 | MAOA (0.35) | TSHRGABRPGABRDGABRA1GABRB1 | |
| Hydrochloric Acid SCHEMBL3719374 | 0.82 | BLM (0.34) | TSHRGABRPGABRDGABRA1GABRB1 | |
| Hydrochloric Acid SCHEMBL27489771 | 0.82 | BLM (0.34) | TSHRGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL17158191 | 0.80 | CA12 (0.47) | TSHRLMNAKDM4EPOLB | |
| SCHEMBL6349353 | 0.79 | KDM4E (0.38) | TSHRGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL6510596 | 0.78 | MAOA (0.32) | ALOX15HSD17B10MAOAMAOB | |
| SCHEMBL22541050 | 0.78 | KDM4E (0.40) | TSHRMAPTKDM4ERAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2940008-B1 | NOVEL BENZAZEPINE DERIVATIVE AND PHARMACEUTICAL USE THEREOF | SANWA KAGAKU KENKYUSHO CO (JP) | 2017-05-17 | — | — | EP | disclosed |
| US-9586905-B2 | Benzoazepine derivative and medical use thereof | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 2017-03-07 | — | — | US | disclosed |
| EP-2940008-A1 | NOVEL BENZAZEPINE DERIVATIVE AND PHARMACEUTICAL USE THEREOF | Sanwa Kagaku Kenkyusho Co., Ltd (JP) | 2015-11-04 | — | — | EP | disclosed |
| US-20150291533-A1 | NOVEL BENZOAZEPINE DERIVATIVE AND MEDICAL USE THEREOF | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 2015-10-15 | — | — | US | disclosed |
| US-6369110-B1 | PROPHYLACTIC AGENT FOR DISEASES CAUSED BY THE ACCELERATION OF THE SODIUM/PROTON EXCHANGE TRANSPORT SYSTEM | SUMITOMO PHARMACEUTICALS COMPANY (JP) | 2002-04-09 | — | — | US | disclosed |
| CN-1282243-A | Pharmaceutical composition containing anilide derivative for antagonizing CCR5 | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2001-01-31 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150291533-A1 | NOVEL BENZOAZEPINE DERIVATIVE AND MEDICAL USE THEREOF | AVPR2, AVPR1A, AVPR1B | TSHR 349/4885GABRP 207/4885GABRD 161/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.