Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29816130 | 0.93 | MAOA (0.35) | MAOAMAOBHSD17B3ALOX15HSD17B10 | |
| SCHEMBL980578 | 0.93 | MAOA (0.35) | MAOAMAOBHSD17B3ALOX15HSD17B10 | |
| Hydrochloric Acid SCHEMBL27489771 | 0.92 | BLM (0.34) | MAOAMAOBHSD17B3ALOX15HSD17B10 | |
| Hydrochloric Acid SCHEMBL3719374 | 0.92 | BLM (0.34) | MAOAMAOBHSD17B3ALOX15HSD17B10 | |
| SCHEMBL32670831 | 0.79 | ALDH1A1 (0.42) | ALOX15HSD17B10 | |
| SCHEMBL28390255 | 0.78 | HSD17B3 (0.40) | HSD17B3ALOX15HSD17B10 | |
| SCHEMBL715561 | 0.78 | HSD17B10 (0.33) | HSD17B3ALOX15HSD17B10 | |
| SCHEMBL30366037 | 0.78 | HSD17B3 (0.40) | HSD17B3ALOX15HSD17B10 | |
| SCHEMBL27719045 | 0.78 | HSD17B3 (0.33) | MAOAMAOBHSD17B3ALOX15HSD17B10 | |
| SCHEMBL7714810 | 0.78 | TSHR (0.39) | MAOAMAOBALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005009970-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF GATIFLOXACIN | MATRIX LABORATORIES LTD (IN) | 2005-02-03 | — | — | WO | claimed |
| WO-2005009970-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF GATIFLOXACIN | MATRIX LABORATORIES LTD (IN) | 2005-02-03 | — | — | WO | disclosed |