Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7717018 | 0.90 | — | — | |
| Hydrochloric Acid SCHEMBL7711406 | 0.89 | SRD5A2 (0.32) | SRD5A2 | |
| Hydrochloric Acid SCHEMBL8161935 | 0.89 | SRD5A2 (0.30) | SRD5A2 | |
| Hydrochloric Acid SCHEMBL7719192 | 0.88 | NPC1 (0.33) | PGR | |
| Hydrochloric Acid SCHEMBL7942049 | 0.84 | PGR (0.31) | PGR | |
| Hydrochloric Acid SCHEMBL7717479 | 0.83 | KDM4E (0.39) | SRD5A2 | |
| Hydrochloric Acid SCHEMBL7716248 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL7934587 | 0.82 | PGR (0.31) | PGR | |
| Hydrochloric Acid SCHEMBL218253 | 0.80 | NPC1 (0.35) | SRD5A2PGR | |
| Hydrochloric Acid SCHEMBL8155468 | 0.80 | MEN1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6372681-B1 | METALLOCENE OF TRANSITION METAL AND; METAL OXIDE, SULFIDE, PHOSPHIDE, CARBIDE, NITRIDE, AND/OR SELENIDE; ORGANOALKALINE EARTH OR ZINC COMPOUND; AND ORGANOALUMINUM COMPOUND | TOSOH CORPORATION (JP) | 2002-04-16 | — | — | US | disclosed |
| US-6121396-A | USING A METALLOCENE HAVING A SUBSTITUTED FLUORENYL GROUP, AND A COMPOUND REACTING WITH THE METALLOCENE TO FORM A CATIONIC METALLOCENE; HIGH- AND NARROW MOLECULAR WEIGHT; NARROW COMPOSITION DISTRIBUTION; PROCESS TEMPERATURE OF >120 C. | TOSOH CORPORATION (JP) | 2000-09-19 | — | — | US | disclosed |
| EP-0942006-A2 | Catalyst for olefin polymer production and process for olefin polymer production employing the catalyst | TOSOH CORPORATION (JP) | 1999-09-15 | — | — | EP | disclosed |
| EP-0709393-A2 | Olefin polymerization catalyst and process for producing olefin polymer | TOSOH CORPORATION (JP) | 1996-05-01 | — | — | EP | disclosed |