Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lithium Ion SCHEMBL28224844 | 0.87 | MEN1 (0.38) | LMNATSHRALDH1A1MAPTPOLB | |
| Dimethoxymethane SCHEMBL27802983 | 0.80 | TSHR (0.37) | TSHR | |
| SCHEMBL2435270 | 0.79 | — | — | |
| SCHEMBL27908638 | 0.79 | ALDH1A1 (0.41) | LMNATSHRALDH1A1MAPT | |
| Lithium Ion SCHEMBL28294852 | 0.79 | CA2 (0.39) | LMNATSHRALDH1A1MAPTPOLB | |
| Nitromethane SCHEMBL28709506 | 0.78 | — | — | |
| SCHEMBL4637926 | 0.75 | — | — | |
| Nitromethane SCHEMBL29707679 | 0.73 | — | — | |
| SCHEMBL251442 | 0.73 | ALDH1A1 (0.33) | TSHRALDH1A1 | |
| Nitromethane SCHEMBL525 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6429297-B1 | DRUG DELIVERY; DIAGNOSIS, THERAPY | UNIVERSITY OF ROCHESTER | 2002-08-06 | — | — | US | disclosed |
| EP-0832111-A4 | MODIFIED AVIDIN AND STREPTAVIDIN AND METHODS OF USE THEREOF | ROSEBROUGH SCOTT F (US) | 1999-03-03 | — | — | EP | disclosed |
| EP-0832111-A1 | MODIFIED AVIDIN AND STREPTAVIDIN AND METHODS OF USE THEREOF | Rosebrough, Scott F. (US) | 1998-04-01 | — | — | EP | disclosed |
| WO-1996040761-A9 | MODIFIED AVIDIN AND STREPTAVIDIN AND METHODS OF USE THEREOF | — | 1997-01-30 | — | — | WO | disclosed |
| WO-1996040761-A1 | MODIFIED AVIDIN AND STREPTAVIDIN AND METHODS OF USE THEREOF | ROSEBROUGH SCOTT F (US) | 1996-12-19 | — | — | WO | disclosed |