Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MERTK | Q12866 | 12/20 | 0.34 |
| ▸ | FLT3 | P36888 | 10/20 | 0.34 |
| ▸ | TYRO3 | Q06418 | 10/20 | 0.34 |
| ▸ | GAS6 | Q14393 | 10/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | DNM2 | P50570 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | AXL | P30530 | 1/20 | 0.31 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6298187 | 0.93 | KMT2A (0.38) | MERTKFLT3TYRO3GAS6KMT2A | |
| SCHEMBL7715499 | 0.91 | KMT2A (0.31) | KMT2A | |
| SCHEMBL6298350 | 0.89 | KMT2A (0.31) | KMT2A | |
| SCHEMBL8183858 | 0.88 | — | — | |
| SCHEMBL6298436 | 0.88 | — | — | |
| SCHEMBL164474 | 0.87 | MERTK (0.34) | MERTKFLT3TYRO3GAS6KMT2A | |
| SCHEMBL7715215 | 0.84 | FLT3 (0.32) | MERTKFLT3TYRO3GAS6KMT2A | |
| SCHEMBL6299669 | 0.83 | KMT2A (0.36) | KMT2A | |
| SCHEMBL6305531 | 0.83 | KMT2A (0.38) | KMT2A | |
| SCHEMBL6300705 | 0.81 | KMT2A (0.36) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6376584-B1 | OXIDATION RESISTANCE, HEAT RESISTANCE, PHOTOSTABILITY | CIBA SPECIALTY CHEMICALS CORPORATION | 2002-04-23 | — | — | US | disclosed |