SCHEMBL6299669

SCHEMBL6299669

CC(C)(O)CON1C(C)(C)CC(CCCCNc2nc(NCCO)nc(NCCCCC3CC(C)(C)N(OCC(C)(C)O)C(C)(C)C3)n2)CC1(C)C

nearest known ligand 0.36

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.36
SLC29A1 Q99808 1/20 0.32
MEN1 O00255 2/20 0.32
GAA P10253 2/20 0.32
GBA1 P04062 4/20 0.31
MAPK1 P28482 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6298436 0.95
SCHEMBL6298350 0.94 KMT2A (0.31) KMT2A
SCHEMBL7715499 0.93 KMT2A (0.31) KMT2A
SCHEMBL6305531 0.90 KMT2A (0.38) KMT2A
SCHEMBL6298187 0.90 KMT2A (0.38) KMT2A
SCHEMBL6300705 0.88 KMT2A (0.36) KMT2A
SCHEMBL9427851 0.85 KMT2A (0.40) KMT2ASLC29A1MEN1GAAGBA1
SCHEMBL9429384 0.84 KMT2A (0.42) KMT2ASLC29A1MEN1GAAGBA1
SCHEMBL6299638 0.84
SCHEMBL7715217 0.83 MERTK (0.34) KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6391949-B1 None US disclosed
US-8729163-B2 Phosphinic acid hydrazide flame retardant compositions BASF SE (DE) 2014-05-20 US disclosed
US-20130137800-A1 PHOSPHINIC ACID HYDRAZIDE FLAME RETARDANT COMPOSITIONS BASF SE (DE) 2013-05-30 US disclosed
US-6872832-B2 Hydroxy substituted N-alkoxy hindered amines and compositions stabilized therewith CIBA SPECIALTY CHEMICALS CORPORATION (US) 2005-03-29 US disclosed
US-20040097620-A1 Flame retardant compositions CIBA SPECIALTY CHEMICALS CORP. 2004-05-20 US disclosed
US-6638997-B2 Used for stabilizing polyolefin and automotive coating formulation against the deleterious effects of oxidative, thermal and actinic radiation CIBA SPECIALTY CHEMICALS CORPORATION 2003-10-28 US disclosed
US-6586507-B2 For stabilizing polyolefins, especially thermoplastic polyolefins, against the deleterious effects of oxidative, thermal and actinic radiation, also for stabilizing acid catalyzed and ambient cured coatings systems CIBA SPECIALTY CHEMICALS CORPORATION 2003-07-01 US disclosed
US-20030120077-A1 Hydroxy substituted N-alkoxy hindered amines and compositions stabilized therewith GALBO JAMES PETER (US) 2003-06-26 US disclosed
US-6420562-B2 OXIDATION, HEAT AND RADIATION RESISTANCE CIBA SPECIALITY CHEMICALS CORPORATION 2002-07-16 US disclosed
US-6420463-B1 HEAT RESISTANCE, OXIDATION RESISTANCE OR PHOTOSTABILITY CIBA SPECIALTY CHEMICALS CORP. 2002-07-16 US disclosed
US-20020058735-A1 Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith GALBO JAMES PETER (US) 2002-05-16 US disclosed
US-6388072-B2 TETRAALKYL SUBSTITUTED PIPERIDINE SUBSTITUTED ON THE N-ATOM WITH O-E-OH GROUP (E= ALKYLENE OR PHENYLENE OR CYCLOALIPHATIC DERIVATIVES) ARE USED FOR STABILIZING POLYOLEFINS AND AUTOMOTIVE COATING AGAINST HEAT, OXIDATION CIBA SPECIALTY CHEMICALS CORPORATION 2002-05-14 US disclosed
US-6380389-B2 FOR POLYOLEFINS AND AUTOMOTIVE COATINGS; LIGHT, HEAT, OXIDATION RESISTANCE CIBA SPECIALTY CHEMICALS CORPORATION 2002-04-30 US disclosed
US-20020040145-A1 Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith GALBO JAMES P (US) 2002-04-04 US disclosed
US-20010034449-A1 Hydroxy-substituted N-Alkoxy hindered amines and compositions stabilized therewith GALBO JAMES P (US) 2001-10-25 US disclosed
US-20010031872-A1 Hydroxy-substituted N-Alkoxy hindered amines and compositions stabilized therewith GALBO JAMES P (US) 2001-10-18 US disclosed
US-20010020099-A1 Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith GALBO JAMES P (US) 2001-09-06 US disclosed
US-20010018520-A1 Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith GALBO JAMES P (US) 2001-08-30 US disclosed
US-20010016658-A1 Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith GALBO JAMES P (US) 2001-08-23 US disclosed
US-6271377-B1 Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith CIBA SPECIALTY CHEMICALS CORPORATION 2001-08-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020040145-A1 Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith POLH, OGG1, OGFOD1 KMT2A 617/4885SLC29A1 2742/4885MEN1 2812/4885
US-20020058735-A1 Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith OGG1, HAO2, POLH KMT2A 609/4885SLC29A1 2605/4885MEN1 2374/4885
US-20010016658-A1 Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith POLH, OGG1, OGFOD1 KMT2A 617/4885SLC29A1 2742/4885MEN1 2812/4885
US-20010034449-A1 Hydroxy-substituted N-Alkoxy hindered amines and compositions stabilized therewith POLH, OGG1, OGFOD1 KMT2A 617/4885SLC29A1 2742/4885MEN1 2812/4885
US-20010020099-A1 Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith POLH, OGG1, OGFOD1 KMT2A 617/4885SLC29A1 2742/4885MEN1 2812/4885
US-20030120077-A1 Hydroxy substituted N-alkoxy hindered amines and compositions stabilized therewith OGG1, POLH, OGFOD1 KMT2A 615/4885SLC29A1 2373/4885MEN1 2478/4885
US-20010018520-A1 Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith POLH, OGG1, OGFOD1 KMT2A 617/4885SLC29A1 2742/4885MEN1 2812/4885
US-20010031872-A1 Hydroxy-substituted N-Alkoxy hindered amines and compositions stabilized therewith POLH, OGG1, OGFOD1 KMT2A 617/4885SLC29A1 2742/4885MEN1 2812/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.