SCHEMBL7715231

SCHEMBL7715231

O=C(c1ccccc1)N(C(=O)c1ccccc1)c1ncnc2c1ncn2[C@H]1C[C@H](O)[C@@H](CO)O1

nearest known ligand 0.57

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 1/20 0.57
LMNA P02545 1/20 0.56
SLC29A1 Q99808 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30694443 0.87 LMNA (0.56) HIF1ALMNA
SCHEMBL29674600 0.81 SLC29A1 (0.59) HIF1ASLC29A1
SCHEMBL21539907 0.81 SLC29A1 (0.59) HIF1ASLC29A1
SCHEMBL22984010 0.81 SLC29A1 (0.59) HIF1ASLC29A1
SCHEMBL14733367 0.81 SLC29A1 (0.59) HIF1ASLC29A1
SCHEMBL264409 0.81 SLC29A1 (0.59) HIF1ASLC29A1
SCHEMBL264408 0.81 SLC29A1 (0.59) HIF1ASLC29A1
SCHEMBL13930530 0.81 SLC29A1 (0.46) HIF1ALMNASLC29A1
SCHEMBL13375777 0.81 SLC29A1 (0.46) HIF1ALMNASLC29A1
SCHEMBL6270350 0.81 HIF1A (0.71) HIF1ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6414137-B1 Selective solvent extraction for the purification of protected nucleosides ALLIEDSIGNAL INC. 2002-07-02 US disclosed
EP-1140957-A1 SELECTIVE SOLVENT EXTRACTION FOR THE PURIFICATION OF PROTECTED NUCLEOSIDES AlliedSignal Inc. (US) 2001-10-10 EP disclosed
WO-2000039138-A1 SELECTIVE SOLVENT EXTRACTION FOR THE PURIFICATION OF PROTECTED NUCLEOSIDES ALLIEDSIGNAL INC. (US) 2000-07-06 WO disclosed