Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | ITGB1 | P05556 | 3/20 | 0.34 |
| ▸ | ITGA4 | P13612 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7715527 | 1.00 | TP53 (0.34) | TP53ITGB1ITGA4ALDH1A1KDM4E | |
| SCHEMBL7716449 | 0.93 | ITGB1 (0.41) | ITGB1ITGA4PTGDR | |
| SCHEMBL7716444 | 0.93 | ITGB1 (0.41) | ITGB1ITGA4PTGDR | |
| SCHEMBL7716446 | 0.93 | ITGB1 (0.41) | ITGB1ITGA4PTGDR | |
| SCHEMBL7714172 | 0.84 | ITGB1 (0.49) | TP53ITGB1ITGA4ALDH1A1PTGDR | |
| SCHEMBL7716171 | 0.84 | TP53 (0.36) | TP53ITGB1ITGA4ALDH1A1KDM4E | |
| SCHEMBL7716181 | 0.84 | TP53 (0.36) | TP53ITGB1ITGA4ALDH1A1KDM4E | |
| SCHEMBL7710679 | 0.83 | ITGB1 (0.42) | TP53ITGB1ITGA4ALDH1A1PTGDR | |
| SCHEMBL7716153 | 0.82 | ELANE (0.40) | TP53ITGB1ITGA4ALDH1A1KDM4E | |
| SCHEMBL7716158 | 0.82 | ELANE (0.40) | TP53ITGB1ITGA4ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403608-B1 | ANTIINFLAMMATORY AND IMMUNE DISORDERS | CELLTECH R&D, LTD. (GB) | 2002-06-11 | — | — | US | disclosed |