Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.34 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 6/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7716171 | 1.00 | TP53 (0.36) | TP53MAPTITGB1ITGA4ELANE | |
| SCHEMBL7714172 | 0.86 | ITGB1 (0.49) | TP53MAPTITGB1ITGA4ELANE | |
| SCHEMBL7710679 | 0.85 | ITGB1 (0.42) | TP53MAPTITGB1ITGA4ELANE | |
| SCHEMBL7715520 | 0.84 | TP53 (0.34) | TP53MAPTITGB1ITGA4ELANE | |
| SCHEMBL7715527 | 0.84 | TP53 (0.34) | TP53MAPTITGB1ITGA4ELANE | |
| SCHEMBL7714210 | 0.81 | ITGB1 (0.42) | ITGB1ITGA4 | |
| SCHEMBL7714207 | 0.81 | ITGB1 (0.42) | ITGB1ITGA4 | |
| SCHEMBL7716185 | 0.80 | TP53 (0.33) | TP53MAPTP2RX3MEN1KMT2A | |
| SCHEMBL7716176 | 0.80 | AKR1C3 (0.36) | TP53MAPTALDH1A1SLC2A1SMN1; SMN2 | |
| SCHEMBL7714205 | 0.79 | ITGB1 (0.58) | ITGB1ITGA4PTGDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403608-B1 | ANTIINFLAMMATORY AND IMMUNE DISORDERS | CELLTECH R&D, LTD. (GB) | 2002-06-11 | — | — | US | disclosed |