Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 3/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.33 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | BTK | Q06187 | 1/20 | 0.31 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.30 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7716444 | 0.85 | ITGB1 (0.41) | — | |
| SCHEMBL7716446 | 0.85 | ITGB1 (0.41) | — | |
| SCHEMBL7716176 | 0.84 | AKR1C3 (0.36) | AKR1C3AKR1C2AKR1C1PTGS1TP53 | |
| SCHEMBL7715520 | 0.81 | TP53 (0.34) | TP53 | |
| SCHEMBL7715530 | 0.81 | ACP1 (0.32) | TP53 | |
| SCHEMBL7710707 | 0.71 | ITGB1 (0.39) | — | |
| SCHEMBL7259930 | 0.71 | ITGB1 (0.42) | — | |
| SCHEMBL5262865 | 0.69 | MAPT (0.33) | — | |
| SCHEMBL7714172 | 0.65 | ITGB1 (0.49) | TP53 | |
| SCHEMBL7718447 | 0.64 | ITGB1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403608-B1 | ANTIINFLAMMATORY AND IMMUNE DISORDERS | CELLTECH R&D, LTD. (GB) | 2002-06-11 | — | — | US | disclosed |